| Gene Symbol |
RETSAT
|
| Entrez Gene |
54884
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
retinol saturase (all-trans-retinol 13,14-reductase)
|
| Other Description |
PPAR-alpha-regulated and starvation-induced gene protein|all-trans-13,14-dihydroretinol saturase|all-trans-retinol 13,14-reductase
|
| Swissprots |
Q96FA4 Q8N2H5 Q53SA9 Q53R95 Q6NUM9 Q6UX05 Q9NXE5 A6NIK3
|
| Accessions |
AAY24096 AAY24126 AFI24910 CAF86585 EAW99530 EAW99531 EAW99532 EAW99533 Q6NUM9 AK000303 BAA91069 AK075261 BAC11505 AK225305 AK296522 BAG59153 AL833237 AY358568 AAQ88931 BC011418 AAH11418 BC068517 AAH68517 BQ448420 DA418052 DB001412 EU831583 ACE87183 EU831668 ACE86502 XR_939688 NM_017750 NP_060220
|
| Function |
Retinol saturase carrying out the saturation of the 13- 14 double bond of all-trans-retinol to produce all-trans-13,14- dihydroretinol. Has activity toward all-trans-retinol as substrate. Does not use all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol isomers as substrates. May play a role in the metabolism of vitamin A (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
| Top Pathways |
Retinol metabolism
|