Gene Symbol | SESN1 |
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Entrez Gene | 27244 |
Alt Symbol | PA26, SEST1 |
Species | Human |
Gene Type | protein-coding |
Description | sestrin 1 |
Other Description | p53 activated gene 26|p53 regulated PA26 nuclear protein|sestrin-1 |
Swissprots | Q9Y6P5 Q9UPD5 Q9Y6P6 Q2M2B7 Q9NV00 Q5T316 |
Accessions | EAW48367 EAW48368 Q9Y6P5 AF033120 AAD04810 AF033121 AAD04811 AF033122 AAD04812 AJ420599 AK001886 BAA91961 AK290157 BAF82846 AK290551 BAF83240 AL133559 BC112036 AAI12037 BC113569 AAI13570 BI549226 BU740021 NM_001199933 NP_001186862 NM_001199934 NP_001186863 NM_014454 NP_055269 |
Function | Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth. {ECO:0000269|PubMed:15105503}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12607115}. |
Top Pathways | p53 signaling pathway |
PA26 CRISPR/Cas9 KO Plasmid (h) - sc-405021 from Santa Cruz Biotechnology
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PA26 HDR Plasmid (h) - sc-405021-HDR from Santa Cruz Biotechnology
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PA26 Double Nickase Plasmid (h) - sc-405021-NIC from Santa Cruz Biotechnology
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PA26 Double Nickase Plasmid (h2) - sc-405021-NIC-2 from Santa Cruz Biotechnology
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PA26 CRISPR Activation Plasmid (h) - sc-405021-ACT from Santa Cruz Biotechnology
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PA26 CRISPR Activation Plasmid (h2) - sc-405021-ACT-2 from Santa Cruz Biotechnology
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PA26 Lentiviral Activation Particles (h) - sc-405021-LAC from Santa Cruz Biotechnology
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PA26 Lentiviral Activation Particles (h2) - sc-405021-LAC-2 from Santa Cruz Biotechnology
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PA26 siRNA (h) - sc-37420 from Santa Cruz Biotechnology
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PA26 shRNA Plasmid (h) - sc-37420-SH from Santa Cruz Biotechnology
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PA26 shRNA (h) Lentiviral Particles - sc-37420-V from Santa Cruz Biotechnology
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SESN1 RNAi - H00027244-R01 from Novus Biologicals
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MISSION® esiRNA - EHU139941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19159 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19159 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08709 from Sigma-Aldrich
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SESN1 siRNA (Human) - CRH9037 from Cohesion Biosciences
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SESN1 - MBS8211574 from MyBioSource
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shRNA set against Human SESN1 (NM_014454.2) - SHH405504 from Creative biogene
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SESN1 shRNA Plasmid (Human) - CHH9037 from Cohesion Biosciences
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SESN1 miRNA 3'UTR clone - MiUTR3H-08219 from Creative biogene
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