Gene Symbol |
SULT2A1
|
Entrez Gene |
6822
|
Alt Symbol |
DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
|
Other Description |
alcohol/hydroxysteroid sulfotransferase|bile salt sulfotransferase|bile-salt sulfotranasferase 2A1
|
Swissprots |
Q06520
|
Accessions |
AAA75491 AAC51353 ACB21041 EAW57516 EAW57517 Q06520 AK289380 BAF82069 AK313415 BAG36209 BC020755 AAH20755 BG563083 BX509490 DQ891165 ABM82091 DQ894346 ABM85272 L02337 L20000 AAA35758 S43859 AAB23169 S43861 U08024 AAA17749 U08025 AAA17750 X70222 CAA49755 X84816 CAA59274 NM_003167 NP_003158
|
Function |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.
|
Top Pathways |
Bile secretion, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450
|