Gene Symbol | UBL4A |
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Entrez Gene | 8266 |
Alt Symbol | DX254E, DXS254E, G6PD, GDX, GET5, MDY2, TMA24, UBL4 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-like 4A |
Other Description | ubiquitin-like 4|ubiquitin-like protein 4A|ubiquitin-like protein GDX |
Swissprots | Q5HY80 P11441 |
Accessions | AAA36790 AAA92650 EAW72700 P11441 AK000405 AK293227 BAG56766 BC020254 BC043346 AAH43346 BC053589 AAH53589 BM711450 CK826435 DA012854 DR003955 HQ448528 ADQ33007 M35604 NM_014235 NP_055050 |
Function | Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting. {ECO:0000269|PubMed:20676083}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:20676083}. |
UBL4A CRISPR/Cas9 KO Plasmid (h) - sc-411130 from Santa Cruz Biotechnology
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UBL4A HDR Plasmid (h) - sc-411130-HDR from Santa Cruz Biotechnology
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UBL4A Double Nickase Plasmid (h) - sc-411130-NIC from Santa Cruz Biotechnology
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UBL4A Double Nickase Plasmid (h2) - sc-411130-NIC-2 from Santa Cruz Biotechnology
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UBL4A CRISPR Activation Plasmid (h) - sc-411130-ACT from Santa Cruz Biotechnology
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UBL4A CRISPR Activation Plasmid (h2) - sc-411130-ACT-2 from Santa Cruz Biotechnology
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UBL4A Lentiviral Activation Particles (h) - sc-411130-LAC from Santa Cruz Biotechnology
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UBL4A Lentiviral Activation Particles (h2) - sc-411130-LAC-2 from Santa Cruz Biotechnology
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UBL4A siRNA (h) - sc-90869 from Santa Cruz Biotechnology
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UBL4A shRNA Plasmid (h) - sc-90869-SH from Santa Cruz Biotechnology
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UBL4A shRNA (h) Lentiviral Particles - sc-90869-V from Santa Cruz Biotechnology
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UBL4A RNAi - H00008266-R01 from Novus Biologicals
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MISSION® esiRNA - EHU052691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22400 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22400 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10557 from Sigma-Aldrich
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UBL4A siRNA (Human) - CRH5416 from Cohesion Biosciences
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UBL4A - MBS828446 from MyBioSource
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shRNA set against Human UBL4A (NM_014235.3) - SHH439360 from Creative biogene
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Human UBL4A siRNA - orb265918 from Biorbyt
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UBL4A shRNA Plasmid (Human) - CHH5416 from Cohesion Biosciences
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UBL4A miRNA 3'UTR clone - MiUTR1H-10962 from Creative biogene
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