Gene Symbol | SLC39A1 |
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Entrez Gene | 27173 |
Alt Symbol | ZIP1, ZIRTL |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 39 (zinc transporter), member 1 |
Other Description | solute carrier family 39 (zinc transporter), member 3|zinc transporter ZIP1|zrt- and Irt-like protein 1 |
Swissprots | Q8N2H7 Q5T4K1 Q9Y380 B4DDY7 Q9NY26 Q9BTV0 Q9Y2Z7 Q9UBI7 |
Accessions | CAB59980 CAF86850 EAW53259 EAW53261 EAW53264 EAW53265 EAW53267 Q9NY26 AF132942 AAD27717 AF151829 AAD34066 AJ243649 CAB59979 AJ271671 CAB82784 AK074943 BAG52035 AK075257 BAC11502 AK293389 BAG56898 AK297983 BAG60292 AK300244 BAG62011 AW571711 BC002563 AAH02563 BC003152 AAH03152 BC007886 AAH07886 BC014303 AAH14303 BC047288 BC069261 BG704399 BM807264 CR457217 CAG33498 DA052424 DA354647 DA711655 DA818910 DB001496 DQ893619 ABM84545 DQ895350 ABM86276 HY042960 NM_001271957 NP_001258886 NM_001271958 NP_001258887 NM_001271959 NP_001258888 NM_001271960 NP_001258889 NM_001271961 NP_001258890 NM_014437 NP_055252 |
Function | Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. {ECO:0000269|PubMed:12888280}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11696349}; Multi-pass membrane protein {ECO:0000269|PubMed:11696349}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:11696349}; Multi-pass membrane protein {ECO:0000269|PubMed:11696349}. Note=Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines. |
Tissue Specificity | Ubiquitous. Expressed in most adult and fetal tissues including the epidermis. {ECO:0000269|PubMed:10610721}. |
ZIP1 CRISPR/Cas9 KO Plasmid (h) - sc-404400 from Santa Cruz Biotechnology
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ZIP1 HDR Plasmid (h) - sc-404400-HDR from Santa Cruz Biotechnology
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ZIP1 Double Nickase Plasmid (h) - sc-404400-NIC from Santa Cruz Biotechnology
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ZIP1 Double Nickase Plasmid (h2) - sc-404400-NIC-2 from Santa Cruz Biotechnology
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ZIP1 CRISPR Activation Plasmid (h) - sc-404400-ACT from Santa Cruz Biotechnology
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ZIP1 CRISPR Activation Plasmid (h2) - sc-404400-ACT-2 from Santa Cruz Biotechnology
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ZIP1 Lentiviral Activation Particles (h) - sc-404400-LAC from Santa Cruz Biotechnology
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ZIP1 Lentiviral Activation Particles (h2) - sc-404400-LAC-2 from Santa Cruz Biotechnology
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ZIP1 siRNA (h) - sc-88210 from Santa Cruz Biotechnology
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ZIP1 shRNA Plasmid (h) - sc-88210-SH from Santa Cruz Biotechnology
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ZIP1 shRNA (h) Lentiviral Particles - sc-88210-V from Santa Cruz Biotechnology
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SLC39A1 RNAi - H00027173-R01 from Novus Biologicals
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MISSION® esiRNA - EHU091531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19614 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19614 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07508 from Sigma-Aldrich
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SLC39A1 siRNA (Human) - CRH9007 from Cohesion Biosciences
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SLC39A1 - MBS8223125 from MyBioSource
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shRNA set against Human SLC39A1 (NM_014437.3) - SHH411052 from Creative biogene
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SLC39A1 shRNA Plasmid (Human) - CHH9007 from Cohesion Biosciences
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SLC39A1 miRNA 3'UTR clone - MiUTR1H-09555 from Creative biogene
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