PRMT7

Gene Symbol	PRMT7
Entrez Gene	54496
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	protein arginine methyltransferase 7
Other Description	[Myelin basic protein]-arginine N-methyltransferase PRMT7|histone-arginine N-methyltransferase PRMT7|myelin basic protein-arginine N-methyltransferase|protein arginine N-methyltransferase 7
Swissprots	Q96PV5 B4E379 B3KUG9 Q9NVM4 Q9H9L0 B3KPR0
Accessions	CAC88319 CAE89471 EAW83224 EAW83225 EAW83226 EAW83227 EAW83228 EAW83229 EAW83230 EAW83231 EAW83232 Q9NVM4 AB067520 BAB67826 AK001502 BAA91726 AK022739 BAB14215 AK056647 BAG51772 AK097175 BAG53431 AK304605 BAG65391 BC000146 AAH00146 CB140365 DA287041 DA648148 XM_005255991 XP_005256048 XM_006721199 XP_006721262 XM_011523112 XP_011521414 XM_011523113 XP_011521415 XM_011523114 XP_011521416 XM_011523115 XP_011521417 XM_011523116 XP_011521418 XM_011523117 XP_011521419 XM_011523118 XP_011521420 XM_011523119 XP_011521421 XM_011523120 XP_011521422 XM_011523121 XP_011521423 XM_011523122 XP_011521424 XM_011523123 XP_011521425 XM_011523124 XP_011521426 XM_011523125 XP_011521427 XM_011523126 XP_011521428 XM_011523127 XP_011521429 XM_011523128 XP_011521430 XM_011523129 XP_011521431 XM_011523130 XP_011521432 XM_011523131 XP_011521433 XR_243413 XR_933336 XR_933339 NM_001184824 NP_001171753 NM_001290018 NP_001276947 NM_019023 NP_061896
Function	Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo. {ECO:0000269|PubMed:15044439, ECO:0000269|PubMed:1
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:15494416}. Nucleus {ECO:0000269|PubMed:15494416}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PRMT7 293T Cell Transient Overexpression Lysate(Denatured) - H00054496-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PRMT7 293 Cell Lysate - 402375 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PRMT7 Overexpression Lysate (Denatured) - H00054496-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

PRMT7 (h): 293 Lysate - sc-110644 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

PRMT7 Over-expression Lysate Product - GWB-8E4D03 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

PRMT7 Overexpression Lysate (Native) - NBL1-14797 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PRMT7 Knockdown Stable Cell Line - CSC-DC012430 from Creative biogene Category Cell Line Species Human

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