Gene Symbol | St8sia1 |
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Entrez Gene | 20449 |
Alt Symbol | 9330109E03Rik, GD3S, Sia-T, Siat8, Siat8a |
Species | Mouse |
Gene Type | protein-coding |
Description | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
Other Description | GD3 synthase|SIAT8-A|ST8Sia I|ST8SiaI|alpha-2, 8-sialyltransferase|alpha-2,8-sialyltransferase 8A|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase|ganglioside GD3 synthase|ganglioside GT3 synthase|sialyltransferase 8 A|sialyltransferase 8A|sialyltransferase St8Sia I|sialytransferase St8Sia I |
Swissprots | Q64687 Q8K1C1 |
Accessions | CAC20706 EDL10653 Q64687 AK039733 BAC30431 AK040548 AK042207 BAE20627 AK046188 BAC32625 AK052444 BAC34994 AK079057 BC024821 AAH24821 BC110671 EF101558 ABK96807 L38677 AAA91869 X84235 CAA59014 XM_006506928 XP_006506991 XM_006506929 XP_006506992 XM_006506930 XP_006506993 XM_011241574 XP_011239876 XM_011241575 XP_011239877 XM_011241576 XP_011239878 NM_011374 NP_035504 |
Function | Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. {ECO:0000269|PubMed:8910600}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - ganglio series |
GD3 synthase CRISPR/Cas9 KO Plasmid (m) - sc-422942 from Santa Cruz Biotechnology
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GD3 synthase HDR Plasmid (m) - sc-422942-HDR from Santa Cruz Biotechnology
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GD3 synthase Double Nickase Plasmid (m) - sc-422942-NIC from Santa Cruz Biotechnology
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GD3 synthase Double Nickase Plasmid (m2) - sc-422942-NIC-2 from Santa Cruz Biotechnology
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GD3 synthase CRISPR Activation Plasmid (m) - sc-422942-ACT from Santa Cruz Biotechnology
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GD3 synthase CRISPR Activation Plasmid (m2) - sc-422942-ACT-2 from Santa Cruz Biotechnology
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GD3 synthase Lentiviral Activation Particles (m) - sc-422942-LAC from Santa Cruz Biotechnology
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GD3 synthase Lentiviral Activation Particles (m2) - sc-422942-LAC-2 from Santa Cruz Biotechnology
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GD3 synthase siRNA (m) - sc-44587 from Santa Cruz Biotechnology
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GD3 synthase shRNA Plasmid (m) - sc-44587-SH from Santa Cruz Biotechnology
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GD3 synthase shRNA (m) Lentiviral Particles - sc-44587-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU078061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN42133 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42133 from Sigma-Aldrich
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ST8SIA1 siRNA (Mouse) - CRM3724 from Cohesion Biosciences
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ST8SIA1 - MBS8218028 from MyBioSource
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shRNA set against Mouse ST8SIA1 (NM_011374.2) - SHH419008 from Creative biogene
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shRNA set against Mouse St8sia1(NM_011374.2) - SHL038834 from Creative biogene
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ST8SIA1 shRNA Plasmid (Mouse) - CHM3724 from Cohesion Biosciences
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ST8SIA1 miRNA 3'UTR clone - MiUTR1M-11287 from Creative biogene
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