Gene Symbol | EIF5B |
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Entrez Gene | 9669 |
Alt Symbol | IF2 |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 5B |
Other Description | eIF-5B|translation initiation factor IF-2|translation initiation factor IF2 |
Swissprots | O95805 O60841 Q53RV7 Q9UF81 Q9UMN7 Q53SI8 |
Accessions | AAX93258 AAY24313 EAX01864 EAX01865 EAX01866 EAX01867 O60841 AB018284 BAA34461 AF078035 AAD16006 AJ006412 CAA07018 AJ006776 CAB44357 AK001386 BAG50898 AK091864 AK308175 AK308176 AL133563 CAB63717 BC006970 AAH06970 BC022260 AAH22260 BC032639 AAH32639 BX485839 NM_015904 NP_056988 |
Function | Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | RNA transport |
eIF5B CRISPR/Cas9 KO Plasmid (h) - sc-406920 from Santa Cruz Biotechnology
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eIF5B HDR Plasmid (h) - sc-406920-HDR from Santa Cruz Biotechnology
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eIF5B Double Nickase Plasmid (h) - sc-406920-NIC from Santa Cruz Biotechnology
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eIF5B Double Nickase Plasmid (h2) - sc-406920-NIC-2 from Santa Cruz Biotechnology
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eIF5B CRISPR Activation Plasmid (h) - sc-406920-ACT from Santa Cruz Biotechnology
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eIF5B CRISPR Activation Plasmid (h2) - sc-406920-ACT-2 from Santa Cruz Biotechnology
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eIF5B Lentiviral Activation Particles (h) - sc-406920-LAC from Santa Cruz Biotechnology
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eIF5B Lentiviral Activation Particles (h2) - sc-406920-LAC-2 from Santa Cruz Biotechnology
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eIF5B siRNA (h) - sc-94706 from Santa Cruz Biotechnology
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eIF5B shRNA Plasmid (h) - sc-94706-SH from Santa Cruz Biotechnology
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eIF5B shRNA (h) Lentiviral Particles - sc-94706-V from Santa Cruz Biotechnology
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Eukaryotic translation initiation factor 5B RNAi - H00009669-R01 from Novus Biologicals
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MISSION® esiRNA - EHU047231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7791 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07038 from Sigma-Aldrich
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EIF5B siRNA (Human) - CRH6443 from Cohesion Biosciences
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EIF5B - MBS8225666 from MyBioSource
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shRNA set against Human EIF5B (NM_015904.3) - SHH284821 from Creative biogene
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shRNA set against Human EIF5B(NM_015904.3) - SHH030463 from Creative biogene
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EIF5B shRNA Plasmid (Human) - CHH6443 from Cohesion Biosciences
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EIF5B miRNA 3'UTR clone - MiUTR1H-03182 from Creative biogene
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