GABRD

Gene Symbol GABRD
Entrez Gene 2563
Alt Symbol EIG10, EJM7, GEFSP5
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, delta
Other Description GABA(A) receptor subunit delta|GABA(A) receptor, delta|GABA-A receptor, delta polypeptide|gamma-aminobutyric acid receptor subunit delta
Swissprots Q8N4N9 O14764
Accessions EAW56137 O14764 AF016917 AAB70007 AI828107 AI936907 AK290861 BAF83550 AW291520 BC033801 AAH33801 BI824761 DA060315 DA064930 DQ892050 ABM82976 XM_011541194 XP_011539496 NM_000815 NP_000806
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction