Gene Symbol | GABRD |
---|---|
Entrez Gene | 2563 |
Alt Symbol | EIG10, EJM7, GEFSP5 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, delta |
Other Description | GABA(A) receptor subunit delta|GABA(A) receptor, delta|GABA-A receptor, delta polypeptide|gamma-aminobutyric acid receptor subunit delta |
Swissprots | Q8N4N9 O14764 |
Accessions | EAW56137 O14764 AF016917 AAB70007 AI828107 AI936907 AK290861 BAF83550 AW291520 BC033801 AAH33801 BI824761 DA060315 DA064930 DQ892050 ABM82976 XM_011541194 XP_011539496 NM_000815 NP_000806 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |