| Gene Symbol |
RALGDS
|
| Entrez Gene |
5900
|
| Alt Symbol |
RGDS, RGF, RalGEF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ral guanine nucleotide dissociation stimulator
|
| Other Description |
ral guanine nucleotide exchange factor
|
| Swissprots |
Q9HAY1 Q6ZSD5 E7ERZ0 B7Z753 Q9P2N8 Q9HCT1 Q9HAX7 Q12967 E7ER93 Q6PCE1 Q6KH11 Q5T7V4
|
| Accessions |
AAG10221 AAG10222 AAG10223 AAG10224 AAG10225 CDL93487 EAW88037 EAW88038 EAW88039 EAW88040 EAW88041 EAW88042 Q12967 AB037729 BAA92546 AF027169 AAQ13414 AF295773 AAG02122 AK000242 AK024575 AK056462 BAG51718 AK074114 BAB84940 AK090450 BAC03431 AK127524 BAC87018 AK301470 BAH13489 BC021581 AAH21581 BC033198 AAH33198 BC040737 BC059362 AAH59362 BM805052 BY797688 DB480866 DC339956 DR003030 GQ129265 ACT64399 GQ129266 ACT64400 HY002335 U14417 AAA52360 NM_001042368 NP_001035827 NM_001271774 NP_001258703 NM_001271775 NP_001258704 NM_001271776 NP_001258705 NM_006266 NP_006257
|
| Function |
Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.
|
| Top Pathways |
Colorectal cancer, Pancreatic cancer, Choline metabolism in cancer, Rap1 signaling pathway
|