| Gene Symbol |
TFPI
|
| Entrez Gene |
100009401
|
| Alt Symbol |
EPI, LACI
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
| Other Description |
extrinsic pathway inhibitor|lipoprotein-associated coagulation inhibitor|tissue factor pathway inhibitor
|
| Swissprots |
P19761 Q28828
|
| Accessions |
P19761 S61902 AAB26836 X54708 CAA38515 XM_008258418 XP_008256640 NM_001101714 NP_001095184
|
| Function |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Complement and coagulation cascades
|