Gene Symbol |
PSMA8
|
Entrez Gene |
143471
|
Alt Symbol |
PSMA7L
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
proteasome (prosome, macropain) subunit, alpha type, 8
|
Other Description |
proteasome subunit alpha type-7-like
|
Swissprots |
B0YJ75 Q8IVP4 Q8TA98 Q8TAA3 Q8TAA2
|
Accessions |
ACA06053 CBF59476 CBU84720 EAX01214 EAX01215 EAX01216 Q8TAA3 BC021713 AAH21713 BC025389 BC025393 BC028371 AAH28371 BC028686 AAH28686 BC042820 AAH42820 BC047355 BI461560 XM_011525818 XP_011524120 XM_011525819 XP_011524121 NM_001025096 NP_001020267 NM_001025097 NP_001020268 NM_001308188 NP_001295117 NM_144662 NP_653263
|
Function |
Component of the spermatoproteasome, a form of the proteasome specifically found in testis that promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
Top Pathways |
Proteasome
|