PLA2G2A

Gene Symbol PLA2G2A
Entrez Gene 5320
Alt Symbol MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
Species Human
Gene Type protein-coding
Description phospholipase A2, group IIA (platelets, synovial fluid)
Other Description GIIC sPLA2|NPS-PLA2|group IIA phospholipase A2|non-pancreatic secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated
Swissprots Q6IBD9 A8K5I7 Q6DN24 P14555 Q9UCD2
Accessions AAA36549 AAG49535 AAK57824 AAK57825 AAM21271 AAR16084 EAW94907 EAW94908 EAW94909 EAW94910 P14555 AK291302 BAF83991 AM393490 CAL38367 AY656695 AAT73043 AY656696 AAT73044 BC005919 AAH05919 BM708748 BU626291 BX641714 CB132375 CR456865 CAG33146 DQ893157 ABM84083 DQ896451 ABM87450 M22430 AAA36550 NM_000300 NP_000291 NM_001161727 NP_001155199 NM_001161728 NP_001155200 NM_001161729 NP_001155201
Function Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
Subcellular Location Membrane; Peripheral membrane protein.
Top Pathways Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism

group II sPLA 2 (G-15) - sc-14468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
group II sPLA<sub>2</sub> (G-15): sc-14468. Western blot analysis of human recombinant PLA<sub>2</sub> Type IIa.

group II sPLA 2 (H-74) - sc-20105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
group II sPLA<sub>2</sub> (H-74): sc-20105. Western blot analysis of group II sPLA<sub>2</sub> expression in mouse lung tissue extract.

group II sPLA 2 (N-16) - sc-14467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

group II sPLA 2 (SCACC353) - sc-58363 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Phospholipase A2 antibody - ab23705 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab23705 at 1/1000 western blot detection of 0.25 ug of human secretory phospolipase A2.

Anti-Phospholipase A2 IIA antibody - ab47105 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Phospholipase A2 IIA antibody [SCACC353] - ab24498 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone SCACC353
Lane 1 :  Precision Plus Protein StandardLanes 2 - 4 :  Anti-Phospholipase A2 IIA antibody [SCACC353] (ab24498) at 5 µg/mlLane 1 : As aboveLane 2 : Human sPLA2 (Type IIa) (0.25 µg)Lane 3 : Human sPLA2 (Type IIa) (0.5 µg)Lane 4 : Human sPLA2 (Type IIa) (1.0 µg)SecondaryLane 2 : Anti-mouse IgG (HRP) conjugate Dilution: 1:10,000Lanes 3 - 4 : (HRP) conjugate Dilution: 1:10,000developed using the ECL technique

Anti-Secretory phospholipase A2 antibody [EPR8650] - ab139692 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8650
All lanes : Anti-Secretory phospholipase A2 antibody [EPR8650] (ab139692) at 1/1000 dilutionLane 1 : A549 cell lysateLane 2 : BxPC3 cell lysateLane 3 : Human placenta cell lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-PLA2G2A / SPLA2 Antibody (aa21-144) - LS-C126134 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-PLA2G2A / SPLA2 Antibody - LS-C211394 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G2A / SPLA2 Antibody (HRP) - LS-C211395 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G2A / SPLA2 Antibody (FITC) - LS-C211396 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G2A / SPLA2 Antibody (Biotin) - LS-C211397 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G2A / SPLA2 Antibody (aa21-144) - LS-C314969 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SPLA2 / PLA2.

Anti-PLA2G2A / SPLA2 Antibody - LS-C335136 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of A549 cell and HeLa cell lysate using PLA2G2A antibody.

Anti-SPLA2 / PLA2 Antibody - LS-C192496 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of PLA2G2A pAb in extracts from A549 and Hela cells.

Anti-PLA2G2A / SPLA2 Antibody IHC-plus™ - LS-B1614 from LifeSpan Bioscience

Prices $395.00
Sizes 1 ea
Host Mouse
Clonality Monoclonal
Anti-PLA2G2A antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1614 concentration 5 ug/ml.

PLA2G2A Antibody (620501) - MAB5374 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 620501
Western blot shows lysates of human spleen tissue. PVDF Membrane was probed with 2 µg/mL of Human PLA2G2A Monoclonal Antibody (Catalog # MAB5374) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PLA2G2A at approximately 17 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.

PLA2G2A Antibody [Unconjugated] - AF5374 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

PLA2G2A Antibody - NB100-57395 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G2A (130-143) antibody produced in rabbit - L0420 from Sigma-Aldrich

Prices $309.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PLA2G2A (130-143): <B>Cat. No. L0420</B>: Immunofluorescence of HUVEC cells using PLA2G2A (130-143), Cat. No. L0420 (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Human PLA2G2A Antibody - AF5374 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep

Human PLA2G2A Affinity Purified Polyclonal Ab, Sheep IgG - AF5374-SP from R&D Systems

Host Sheep
Clonality Polyclonal

Human PLA2G2A Antibody - MAB5374 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 620501
Detection of Human PLA2G2A by Western Blot. Western blot shows lysates of human spleen tissue. PVDF Membrane was probed with 2 µg/mL of Human PLA2G2A Monoclonal Antibody (Catalog # MAB5374) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). A specific band was detected for PLA2G2A at approximately 17 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1 .

Human PLA2G2A MAb (Clone 620501), Mouse IgG2B - MAB5374-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 620501
Detection of Human PLA2G2A by Western Blot. Western blot shows lysates of human spleen tissue. PVDF Membrane was probed with 2 µg/mL of Human PLA2G2A Monoclonal Antibody (Catalog # MAB5374) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for PLA2G2A at approximately 17 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
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