| Gene Symbol | PLA2G2A |
|---|---|
| Entrez Gene | 5320 |
| Alt Symbol | MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IIA (platelets, synovial fluid) |
| Other Description | GIIC sPLA2|NPS-PLA2|group IIA phospholipase A2|non-pancreatic secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated |
| Swissprots | Q6IBD9 A8K5I7 Q6DN24 P14555 Q9UCD2 |
| Accessions | AAA36549 AAG49535 AAK57824 AAK57825 AAM21271 AAR16084 EAW94907 EAW94908 EAW94909 EAW94910 P14555 AK291302 BAF83991 AM393490 CAL38367 AY656695 AAT73043 AY656696 AAT73044 BC005919 AAH05919 BM708748 BU626291 BX641714 CB132375 CR456865 CAG33146 DQ893157 ABM84083 DQ896451 ABM87450 M22430 AAA36550 NM_000300 NP_000291 NM_001161727 NP_001155199 NM_001161728 NP_001155200 NM_001161729 NP_001155201 |
| Function | Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. |
| Subcellular Location | Membrane; Peripheral membrane protein. |
| Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |