Gene Symbol | LMTK2 |
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Entrez Gene | 22853 |
Alt Symbol | AATYK2, BREK, KPI-2, KPI2, LMR2, PPP1R100, cprk |
Species | Human |
Gene Type | protein-coding |
Description | lemur tyrosine kinase 2 |
Other Description | CDK5/p35-regulated kinase|apoptosis-associated tyrosine kinase 2|brain-enriched kinase|cyclin-dependent kinase 5/p35-regulated kinase|hBREK|kinase phosphatase inhibitor 2|kinase/phosphatase/inhibitor 2|protein phosphatase 1, regulatory subunit 100|serine/threonine-protein kinase KPI-2|serine/threonine-protein kinase LMTK2 |
Swissprots | Q75MG7 A4D272 Q8IWU2 Q9UPS3 |
Accessions | AAS07515 CAM91184 CCQ43469 EAL23894 EAW76719 EAW76720 EAW76721 Q8IWU2 AB029002 BAA83031 AK128506 AW183515 AY130988 AAN08717 BC080576 BC131504 AAI31505 BC146773 BC167828 AAI67828 BE049530 BF001752 BM172505 XM_011515981 XP_011514283 NM_014916 NP_055731 |
Function | Phosphorylates PPP1C, phosphorylase b and CFTR. |
Subcellular Location | Membrane {ECO:0000269|PubMed:23114966}; Multi-pass membrane protein {ECO:0000269|PubMed:23114966}. |
Tissue Specificity | Mainly expressed in skeletal muscle, and weakly in brain and pancreas. {ECO:0000269|PubMed:12393858}. |
KPI-2 CRISPR/Cas9 KO Plasmid (h) - sc-411620 from Santa Cruz Biotechnology
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KPI-2 HDR Plasmid (h) - sc-411620-HDR from Santa Cruz Biotechnology
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KPI-2 Double Nickase Plasmid (h) - sc-411620-NIC from Santa Cruz Biotechnology
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KPI-2 Double Nickase Plasmid (h2) - sc-411620-NIC-2 from Santa Cruz Biotechnology
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KPI-2 CRISPR Activation Plasmid (h) - sc-411620-ACT from Santa Cruz Biotechnology
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KPI-2 CRISPR Activation Plasmid (h2) - sc-411620-ACT-2 from Santa Cruz Biotechnology
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KPI-2 Lentiviral Activation Particles (h) - sc-411620-LAC from Santa Cruz Biotechnology
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KPI-2 Lentiviral Activation Particles (h2) - sc-411620-LAC-2 from Santa Cruz Biotechnology
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KPI-2 siRNA (h) - sc-75397 from Santa Cruz Biotechnology
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KPI-2 shRNA Plasmid (h) - sc-75397-SH from Santa Cruz Biotechnology
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KPI-2 shRNA (h) Lentiviral Particles - sc-75397-V from Santa Cruz Biotechnology
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LMTK2 RNAi - H00022853-R02 from Novus Biologicals
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MISSION® siRNA - SIHK1056 from Sigma-Aldrich
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MISSION® siRNA - SIHK1058 from Sigma-Aldrich
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MISSION® siRNA - SIHK1057 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2404 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2404 from Sigma-Aldrich
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LMTK2 siRNA (Human) - CRH7814 from Cohesion Biosciences
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shRNA set against Human LMTK2 (NM_014916.3) - SHH331127 from Creative biogene
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LMTK2 shRNA Plasmid (Human) - CHH7814 from Cohesion Biosciences
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LMTK2 miRNA 3'UTR clone - MiUTR4H-TG05101 from Creative biogene
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