| Gene Symbol |
SMOC1
|
| Entrez Gene |
64093
|
| Alt Symbol |
OAS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SPARC related modular calcium binding 1
|
| Other Description |
SPARC-related modular calcium-binding protein 1|secreted modular calcium-binding protein 1
|
| Swissprots |
Q9H4F8 Q96F78 A8K1S3 B2R7P5
|
| Accessions |
EAW81013 EAW81014 EAW81015 EAW81016 Q9H4F8 AJ249900 CAC10352 AK098441 AK289988 BAF82677 AK313063 BAG35892 BC008608 AAH08608 BC011548 AAH11548 BQ183777 BX110623 DA805236 DQ891783 ABM82709 DQ894967 ABM85893 XM_005267995 XP_005268052 XM_005267996 XP_005268053 NM_001034852 NP_001030024 NM_022137 NP_071420
|
| Function |
Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. {ECO:0000269|PubMed:20359165, ECO:0000269|PubMed:21194678, ECO:0000269|PubMed:21194680}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:12130637, ECO:0000269|PubMed:20359165}. Note=In or around the basement membrane.
|
| Tissue Specificity |
Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen. {ECO:0000269|PubMed:12130637}.
|
![Western Blot: SMOC1 Overexpression Lysate (Adult Normal) [NBL1-16246] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SMOC1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/786_SMOC1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16246-img0002.jpg)