APOE

Gene Symbol	APOE
Entrez Gene	348
Alt Symbol	AD2, APO-E, LDLCQ5, LPG
Species	Human
Gene Type	protein-coding
Description	apolipoprotein E
Other Description	apolipoprotein E3
Swissprots	Q9P2S4 P02649 C0JYY5 B2RC15
Accessions	AAB59397 AAD02505 AAG27089 AAL82810 ACN81314 ADK26133 AFS60672 BAA96080 CAA63051 EAW57306 P02649 AK308546 AK314898 BAG37412 AL037046 BC003557 AAH03557 BI550631 BM042032 BU848796 CA771535 DB486513 DQ892548 ABM83474 DQ895759 ABM86685 HY056112 HY074384 HY074888 K00396 AAB59546 M12529 AAB59518 X00199 CAA25017 Z70760 CAA94806 NM_000041 NP_000032 NM_001302688 NP_001289617 NM_001302689 NP_001289618 NM_001302690 NP_001289619 NM_001302691 NP_001289620
Function	Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Subcellular Location	Secreted.
Tissue Specificity	Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
Top Pathways	Alzheimer's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Apolipoprotein E3 full length protein - ab123764 from Abcam Category Protein Prices $192.00 Sizes 100 µg Source E. coli Species Human

Apolipoprotein E peptide (305-317) - ab45715 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human Apolipoprotein E full length protein - ab55210 from Abcam Category Protein Prices $297.00 Sizes 500 µg Source E. coli Species Human

Human Apolipoprotein E full length protein - ab167817 from Abcam Category Protein Prices $609.00 Sizes 50 µg Source Native Species Human

Human Apolipoprotein E full length protein - ab123749 from Abcam Category Protein Prices $188.00 Sizes 100 µg Source E. coli Species Human

Human Apolipoprotein E full length protein - ab91027 from Abcam Category Protein Prices $522.00 Sizes 50 µg Source Native Species Human

Human Apolipoprotein E full length protein - ab50244 from Abcam Category Protein Prices $110.00, $235.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human Apolipoprotein E peptide - ab93496 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Apolipoprotein E full length protein - ab196069 from Abcam Category Protein Prices $359.00 Sizes 10 µg Source HEK 293 cells Species Human

Human Apolipoprotein E3 full length protein - ab50242 from Abcam Category Protein Prices $235.00 Sizes 500 µg Source E. coli Species Human

Human Apolipoprotein E4 full length protein - ab50243 from Abcam Category Protein Prices $235.00 Sizes 500 µg Source E. coli Species Human

Human Apolipoprotein E4 full length protein - ab123766 from Abcam Category Protein Prices $188.00 Sizes 100 µg Source E. coli Species Human

Human VLDL full length protein - ab91126 from Abcam Category Protein Source Native Species Human

Human VLDL full length protein - ab167806 from Abcam Category Protein Source Native Species Human

Human VLDL full length protein - ab78489 from Abcam Category Protein Source Native Species Human

APOE / Apolipoprotein E Antibody Blocking Peptide - LS-E19527 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOE / Apolipoprotein E Antibody Blocking Peptide - LS-E19526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOE / Apolipoprotein E Antibody Blocking Peptide - LS-E31434 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APOE / Apolipoprotein E Antibody Blocking Peptide - LS-E25851 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOE / Apolipoprotein E Antibody Blocking Peptide - LS-E9077 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Apolipoprotein E/ApoE Protein - NBP1-99157 from Novus Biologicals Category Protein Prices $90.00 Sizes 100 µg Source E. coli Species Human

Recombinant Human Apolipoprotein E/ApoE Protein - NBP1-99158 from Novus Biologicals Category Protein Prices $80.00 Sizes 100 µg Source E. coli Species Human

ApoE4 Protein - NBP1-99156 from Novus Biologicals Category Protein Species Human

Apolipoprotein E/ApoE Protein - NBP1-99128 from Novus Biologicals Category Protein Species Human

Apolipoprotein E/ApoE Protein - NBP1-99127 from Novus Biologicals Category Protein Species Human

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