Gene Symbol | ABCD3 |
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Entrez Gene | 5825 |
Alt Symbol | ABC43, CBAS5, PMP70, PXMP1, ZWS2 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family D (ALD), member 3 |
Other Description | 70 kDa peroxisomal membrane protein|ATP-binding cassette sub-family D member 3|Peroxisomal membrane protein-1 (70kD)|dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))|peroxisomal membrane protein 1 (70kD, Zellweger syndrome) |
Swissprots | Q6NUN5 D3DT46 Q15271 P28288 Q9H529 Q96DA3 |
Accessions | CAA58470 EAW73046 EAW73047 EAW73048 EAW73049 EAW73050 P28288 AK126440 AK296791 BAG59369 AK302714 BAG63934 AK308159 BC009712 AAH09712 BC068509 AAH68509 BT006644 AAP35290 BX648715 DC317792 M81182 AAA60128 X58528 CAA41416 XM_005271089 XP_005271146 XM_006710802 XP_006710865 XM_011541877 XP_011540179 NM_001122674 NP_001116146 NM_002858 NP_002849 |
Function | Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. {ECO:0000269|PubMed:11248239}. |
Subcellular Location | Peroxisome membrane {ECO:0000269|PubMed:10704444}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10704444}. |
Top Pathways | ABC transporters, Peroxisome |
ABCD3 CRISPR/Cas9 KO Plasmid (h) - sc-407199 from Santa Cruz Biotechnology
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ABCD3 HDR Plasmid (h) - sc-407199-HDR from Santa Cruz Biotechnology
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ABCD3 Double Nickase Plasmid (h) - sc-407199-NIC from Santa Cruz Biotechnology
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ABCD3 Double Nickase Plasmid (h2) - sc-407199-NIC-2 from Santa Cruz Biotechnology
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ABCD3 CRISPR Activation Plasmid (h) - sc-407199-ACT from Santa Cruz Biotechnology
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ABCD3 CRISPR Activation Plasmid (h2) - sc-407199-ACT-2 from Santa Cruz Biotechnology
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ABCD3 Lentiviral Activation Particles (h) - sc-407199-LAC from Santa Cruz Biotechnology
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ABCD3 Lentiviral Activation Particles (h2) - sc-407199-LAC-2 from Santa Cruz Biotechnology
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ABCD3 siRNA (h) - sc-41147 from Santa Cruz Biotechnology
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ABCD3 shRNA Plasmid (h) - sc-41147-SH from Santa Cruz Biotechnology
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ABCD3 shRNA (h) Lentiviral Particles - sc-41147-V from Santa Cruz Biotechnology
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PMP70 RNAi - H00005825-R02 from Novus Biologicals
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MISSION® esiRNA - EHU078831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2642 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2642 from Sigma-Aldrich
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ABCD3 siRNA (Human) - CRH3937 from Cohesion Biosciences
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ABCD3 - MBS8217200 from MyBioSource
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shRNA set against Human ABCD3 (NM_002858.3) - SHH229222 from Creative biogene
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Human ABCD3 siRNA - orb264439 from Biorbyt
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ABCD3 shRNA Plasmid (Human) - CHH3937 from Cohesion Biosciences
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ABCD3 miRNA 3'UTR clone - MiUTR3H-01694 from Creative biogene
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ABCD3 miRNA 3'UTR clone - MiUTR3H-01695 from Creative biogene
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