| Gene Symbol |
PIBF1
|
| Entrez Gene |
10464
|
| Alt Symbol |
C13orf24, CEP90, PIBF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
progesterone immunomodulatory binding factor 1
|
| Other Description |
progesterone-induced blocking factor 1|progesterone-induced-blocking factor 1
|
| Swissprots |
O95664 Q96SF4 Q6U9V2 Q86V07 Q6UG50 Q8WXW3
|
| Accessions |
CAA70844 EAW80522 EAW80523 Q8WXW3 AF330046 AAL37481 AK309828 AY370776 AAQ73282 AY375528 AAQ67659 BC006009 AAH06009 BC008432 BC041806 AAH41806 BC051911 AAH51911 BG201462 BX341357 XM_006719755 XP_006719818 XM_011534881 XP_011533183 XM_011534882 XP_011533184 XM_011534883 XP_011533185 XM_011534884 XP_011533186 XM_011534885 XP_011533187 XM_011534886 XP_011533188 XR_941461 NM_006346 NP_006337
|
| Function |
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.
|
| Tissue Specificity |
Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon. {ECO:0000269|PubMed:11935316}.
|