Gene Symbol | LCA5 |
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Entrez Gene | 167691 |
Alt Symbol | C6orf152 |
Species | Human |
Gene Type | protein-coding |
Description | Leber congenital amaurosis 5 |
Other Description | Lebercilin|leber congenital amaurosis 5 protein |
Swissprots | E1P542 Q86VQ0 Q9BWX7 |
Accessions | EAW48705 EAW48706 Q86VQ0 AK299314 BAG61324 AL832214 BC050327 AAH50327 BE883302 BX648161 CF890814 JF432392 ADZ15609 XM_005248665 XP_005248722 XM_011535504 XP_011533806 NM_001122769 NP_001116241 NM_181714 NP_859065 |
Function | Might be involved in minus end-directed microtubule transport. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17546029}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:17546029}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:17546029}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17546029}. Note=In non- ciliated cells, localizes to the centrosome and its associated microtubule array. |
LCA5 CRISPR/Cas9 KO Plasmid (h) - sc-414901 from Santa Cruz Biotechnology
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LCA5 HDR Plasmid (h) - sc-414901-HDR from Santa Cruz Biotechnology
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LCA5 Double Nickase Plasmid (h) - sc-414901-NIC from Santa Cruz Biotechnology
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LCA5 Double Nickase Plasmid (h2) - sc-414901-NIC-2 from Santa Cruz Biotechnology
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LCA5 CRISPR Activation Plasmid (h) - sc-414901-ACT from Santa Cruz Biotechnology
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LCA5 CRISPR Activation Plasmid (h2) - sc-414901-ACT-2 from Santa Cruz Biotechnology
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LCA5 Lentiviral Activation Particles (h) - sc-414901-LAC from Santa Cruz Biotechnology
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LCA5 Lentiviral Activation Particles (h2) - sc-414901-LAC-2 from Santa Cruz Biotechnology
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LCA5 siRNA (h) - sc-95465 from Santa Cruz Biotechnology
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LCA5 shRNA Plasmid (h) - sc-95465-SH from Santa Cruz Biotechnology
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LCA5 shRNA (h) Lentiviral Particles - sc-95465-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11577 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11577 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10845 from Sigma-Aldrich
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LCA5 siRNA (Human) - CRJ6062 from Cohesion Biosciences
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shRNA set against Human LCA5 (NM_181714.3) - SHH328783 from Creative biogene
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LCA5 shRNA Plasmid (Human) - CHJ6062 from Cohesion Biosciences
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