Gene Symbol | CCT5 |
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Entrez Gene | 22948 |
Alt Symbol | CCT-epsilon, CCTE, HEL-S-69, PNAS-102, TCP-1-epsilon |
Species | Human |
Gene Type | protein-coding |
Description | chaperonin containing TCP1, subunit 5 (epsilon) |
Other Description | T-complex protein 1 subunit epsilon|epididymis secretory protein Li 69 |
Swissprots | A8K2X8 P48643 B4DYD8 A8JZY8 |
Accessions | EAX08072 P48643 AF275798 AAG23814 AI290125 AI470998 AJ012489 AK289353 BAF82042 AK290393 BAF83082 AK293341 BAG56857 AK293437 BAG56941 AK301760 BAG63220 AK301985 BAG63393 AK302368 BAG63690 AK302383 BAG63700 AK303086 BAG64197 AK303147 BAG64251 AK316376 BAH14747 BC002971 AAH02971 BC006543 AAH06543 BC009454 AAH09454 BC035499 AAH35499 BC040027 BU858349 D43950 BAA07894 DB449481 DC368224 DC395133 DQ892743 ABM83669 DQ895989 ABM86942 FJ224303 ACI45995 XM_011513991 XP_011512293 NM_001306153 NP_001293082 NM_001306154 NP_001293083 NM_001306155 NP_001293084 NM_001306156 NP_001293085 NM_012073 NP_036205 |
Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20080638}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20080638}. |
TCP-1 ε siRNA (h) - sc-43447 from Santa Cruz Biotechnology
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TCP-1 ε shRNA Plasmid (h) - sc-43447-SH from Santa Cruz Biotechnology
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TCP-1 ε shRNA (h) Lentiviral Particles - sc-43447-V from Santa Cruz Biotechnology
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CCT5 RNAi - H00022948-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5668 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5668 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09790 from Sigma-Aldrich
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CCT5 siRNA (Human) - CRH7893 from Cohesion Biosciences
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CCT5 - MBS8213878 from MyBioSource
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shRNA set against Human CCT5 (NM_012073.3) - SHH258341 from Creative biogene
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shRNA set against Human CCT5(NM_012073.3) - SHG154138 from Creative biogene
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Human CCT5 siRNA - orb268395 from Biorbyt
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CCT5 shRNA Plasmid (Human) - CHH7893 from Cohesion Biosciences
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CCT5 miRNA 3'UTR clone - MiUTR1H-01834 from Creative biogene
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