Gene Symbol | PPCS |
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Entrez Gene | 79717 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phosphopantothenoylcysteine synthetase |
Other Description | PPC synthetase|phosphopantothenate--cysteine ligase |
Swissprots | Q9HAB8 Q3KQT2 Q5VVM0 |
Accessions | EAX07158 Q9HAB8 AA748446 AK021900 BAB13931 BC012383 BC062586 BC104938 AAI04939 BC106064 AAI06065 BC112015 AAI12016 BJ990298 BM923950 BP211065 BP872074 CB998485 DB479832 XR_946757 NM_001077447 NP_001070915 NM_001287506 NP_001274435 NM_001287507 NP_001274436 NM_001287508 NP_001274437 NM_001287509 NP_001274438 NM_001287510 NP_001274439 NM_001287511 NP_001274440 NM_024664 NP_078940 |
Function | Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. {ECO:0000269|PubMed:11923312, ECO:0000269|PubMed:12906824}. |
Top Pathways | Pantothenate and CoA biosynthesis |
PPC Synthetase CRISPR/Cas9 KO Plasmid (h) - sc-413222 from Santa Cruz Biotechnology
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PPC Synthetase HDR Plasmid (h) - sc-413222-HDR from Santa Cruz Biotechnology
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PPC Synthetase Double Nickase Plasmid (h) - sc-413222-NIC from Santa Cruz Biotechnology
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PPC Synthetase Double Nickase Plasmid (h2) - sc-413222-NIC-2 from Santa Cruz Biotechnology
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PPC Synthetase CRISPR Activation Plasmid (h) - sc-413222-ACT from Santa Cruz Biotechnology
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PPC Synthetase CRISPR Activation Plasmid (h2) - sc-413222-ACT-2 from Santa Cruz Biotechnology
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PPC Synthetase Lentiviral Activation Particles (h) - sc-413222-LAC from Santa Cruz Biotechnology
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PPC Synthetase Lentiviral Activation Particles (h2) - sc-413222-LAC-2 from Santa Cruz Biotechnology
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PPC Synthetase siRNA (h) - sc-88373 from Santa Cruz Biotechnology
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PPC Synthetase shRNA Plasmid (h) - sc-88373-SH from Santa Cruz Biotechnology
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PPC Synthetase shRNA (h) Lentiviral Particles - sc-88373-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU111831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17208 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17208 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04086 from Sigma-Aldrich
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PPCS siRNA (Human) - CRJ2510 from Cohesion Biosciences
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shRNA set against Human PPCS (NM_001077447.1) - SHH380424 from Creative biogene
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shRNA set against Human PPCS(NM_024664.2) - SHR131268 from Creative biogene
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shRNA set against Human PPCS(NM_001077447.1) - SHR131286 from Creative biogene
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Human PPCS siRNA - orb273011 from Biorbyt
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PPCS shRNA Plasmid (Human) - CHJ2510 from Cohesion Biosciences
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PPCS miRNA 3'UTR clone - MiUTR1H-08137 from Creative biogene
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PPCS miRNA 3'UTR clone - MiUTR1H-08138 from Creative biogene
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