| Gene Symbol |
OLA1
|
| Entrez Gene |
29789
|
| Alt Symbol |
DOC45, GBP45, GTBP9, GTPBP9, PTD004
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Obg-like ATPase 1
|
| Other Description |
DNA damage-regulated overexpressed in cancer 45 protein|GTP-binding protein 9 (putative)|GTP-binding protein PTD004|homologous yeast-44.2 protein|obg-like ATPase 1
|
| Swissprots |
Q9P1D3 Q96CU1 Q8NCI8 Q9UNY9 D7EHM2 Q5BJD7 Q9NTK5 Q96SV2 Q9Y6G4
|
| Accessions |
AAY14779 AAY14876 CAF85894 EAX11149 EAX11150 EAX11151 Q9NTK5 AF078859 AAD44491 AF078868 AAD44500 AF116703 AAF71123 AF134478 AAP97255 AK027523 BAB55174 AK074710 BAC11153 AK225112 AK225138 AK296339 BAG59026 AL136546 CAB66481 AL833441 BC012842 AAH12842 BC013925 AAH13925 BC029376 AAH29376 BC068447 BC091522 AAH91522 DQ250006 ABB72766 NM_001011708 NP_001011708 NM_013341 NP_037473
|
| Function |
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:20053727}. Nucleus {ECO:0000255|HAMAP- Rule:MF_03167, ECO:0000269|PubMed:20053727}. Nucleus, nucleolus {ECO:0000255|HAMAP-Rule:MF_03167, ECO:0000269|PubMed:20053727}. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm.
|
| Tissue Specificity |
Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.
|