| Gene Symbol | SEC31A |
|---|---|
| Entrez Gene | 22872 |
| Alt Symbol | ABP125, ABP130, HSPC275, HSPC334, SEC31L1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | SEC31 homolog A (S. cerevisiae) |
| Other Description | SEC31-like protein 1|SEC31-related protein A|protein transport protein Sec31A|web1-like protein|yeast Sec31p homolog |
| Swissprots | Q6ZU90 Q9UM06 Q9P0A6 O94979 Q9UM05 B7ZL00 Q7LCX9 Q5H9P6 Q9P048 Q8IZH4 Q659G7 Q5XG74 Q17RR5 B4DIW6 B7ZKZ7 H7C2W3 Q86TJ0 |
| Accessions | EAX05906 EAX05907 EAX05908 EAX05909 EAX05910 EAX05911 EAX05912 O94979 AB018358 BAA84923 AB018359 BAA84924 AB020712 BAA74928 AF139184 AAF67836 AF161393 AAF28953 AF161452 AAF29012 AK001014 AK002161 AK125897 BAC86336 AK225934 AK295810 BAG58628 AL049463 CAH56418 AL704825 AY137583 AAN15221 BC031292 BC039834 BC047883 AAH47883 BC084583 AAH84583 BC117221 AAI17222 BC143489 AAI43490 BC143491 AAI43492 BC143492 AAI43493 CA397330 CA428539 CR933696 CAI45995 DA218900 DA508741 DA720299 DC342364 XM_005262850 XP_005262907 XM_011531746 XP_011530048 XM_011531747 XP_011530049 XM_011531748 XP_011530050 XM_011531749 XP_011530051 NM_001077206 NP_001070674 NM_001077207 NP_001070675 NM_001077208 NP_001070676 NM_001191049 NP_001177978 NM_001300744 NP_001287673 NM_001300745 NP_001287674 NM_014933 NP_055748 NM_016211 NP_057295 |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associates with membranes in a GTP-dependent manner. {ECO:0000250}. |
| Tissue Specificity | Abundantly and ubiquitously expressed. {ECO:0000269|PubMed:10574704, ECO:0000269|PubMed:10788476}. |
| Top Pathways | Protein processing in endoplasmic reticulum |
Sec31A CRISPR/Cas9 KO Plasmid (h) - sc-403938 from Santa Cruz Biotechnology
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Sec31A HDR Plasmid (h) - sc-403938-HDR from Santa Cruz Biotechnology
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Sec31A Double Nickase Plasmid (h) - sc-403938-NIC from Santa Cruz Biotechnology
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Sec31A Double Nickase Plasmid (h2) - sc-403938-NIC-2 from Santa Cruz Biotechnology
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Sec31A CRISPR Activation Plasmid (h) - sc-403938-ACT from Santa Cruz Biotechnology
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Sec31A CRISPR Activation Plasmid (h2) - sc-403938-ACT-2 from Santa Cruz Biotechnology
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Sec31A Lentiviral Activation Particles (h) - sc-403938-LAC from Santa Cruz Biotechnology
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Sec31A Lentiviral Activation Particles (h2) - sc-403938-LAC-2 from Santa Cruz Biotechnology
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Sec31A siRNA (h) - sc-89169 from Santa Cruz Biotechnology
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Sec31A shRNA Plasmid (h) - sc-89169-SH from Santa Cruz Biotechnology
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Sec31A shRNA (h) Lentiviral Particles - sc-89169-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU139891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19037 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19037 from Sigma-Aldrich
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SEC31A siRNA (Human) - CRH7829 from Cohesion Biosciences
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SEC31A - MBS8239261 from MyBioSource
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shRNA set against Human SEC31A (NM_014933.3) - SHH403852 from Creative biogene
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SEC31A shRNA Plasmid (Human) - CHH7829 from Cohesion Biosciences
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SEC31A miRNA 3'UTR clone - MiUTR3H-11109 from Creative biogene
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SEC31A miRNA 3'UTR clone - MiUTR3H-11110 from Creative biogene
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SEC31A miRNA 3'UTR clone - MiUTR3H-11111 from Creative biogene
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SEC31A miRNA 3'UTR clone - MiUTR3H-11112 from Creative biogene
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SEC31A miRNA 3'UTR clone - MiUTR3H-11113 from Creative biogene
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