| Gene Symbol |
SHOX
|
| Entrez Gene |
6473
|
| Alt Symbol |
GCFX, PHOG, SHOXY, SS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
short stature homeobox
|
| Other Description |
growth control factor, X-linked|pseudoautosomal homeobox-containing osteogenic protein|short stature homeobox protein
|
| Swissprots |
O00412 O15267 O00413 O15266
|
| Accessions |
AAT46026 EAW66815 EAW66816 EAW66817 O15266 BC141503 AAI41504 BC148783 AAI48784 U89331 AAC18820 Y11535 CAA72298 Y11536 CAA72299 NM_000451 NP_000442 NM_006883 NP_006874
|
| Function |
Controls fundamental aspects of growth and development.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}.
|
| Tissue Specificity |
SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
|