| Gene Symbol | BMP7 |
|---|---|
| Entrez Gene | 655 |
| Alt Symbol | OP-1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | bone morphogenetic protein 7 |
| Other Description | osteogenic protein 1 |
| Swissprots | Q9NTQ7 P18075 Q9H512 |
| Accessions | AAF97256 AAG43508 AAM93281 CAG17752 CAJ29673 CAJ47525 CAJ86525 CAJ98562 CAL47728 CAL85403 CAP07469 CAV07685 CBI69260 CDH92867 EAW75529 EAW75530 EAW75531 P18075 AK094784 AK291186 BAF83875 AK312419 BAG35329 BC004248 BC008584 AAH08584 BM683430 DA740733 DQ891494 ABM82420 DQ894685 ABM85611 EU176612 ABW03413 EU679366 ACD50899 KJ875974 AIL24690 M60316 AAA36738 X51801 CAA36100 NM_001719 NP_001710 |
| Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Expressed in the kidney and bladder. Lower levels seen in the brain. |
| Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway |