Gene Symbol | BMP7 |
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Entrez Gene | 655 |
Alt Symbol | OP-1 |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein 7 |
Other Description | osteogenic protein 1 |
Swissprots | Q9NTQ7 P18075 Q9H512 |
Accessions | AAF97256 AAG43508 AAM93281 CAG17752 CAJ29673 CAJ47525 CAJ86525 CAJ98562 CAL47728 CAL85403 CAP07469 CAV07685 CBI69260 CDH92867 EAW75529 EAW75530 EAW75531 P18075 AK094784 AK291186 BAF83875 AK312419 BAG35329 BC004248 BC008584 AAH08584 BM683430 DA740733 DQ891494 ABM82420 DQ894685 ABM85611 EU176612 ABW03413 EU679366 ACD50899 KJ875974 AIL24690 M60316 AAA36738 X51801 CAA36100 NM_001719 NP_001710 |
Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in the kidney and bladder. Lower levels seen in the brain. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway |
BMP-7 CRISPR/Cas9 KO Plasmid (h) - sc-401160 from Santa Cruz Biotechnology
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BMP-7 HDR Plasmid (h) - sc-401160-HDR from Santa Cruz Biotechnology
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BMP-7 Double Nickase Plasmid (h) - sc-401160-NIC from Santa Cruz Biotechnology
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BMP-7 Double Nickase Plasmid (h2) - sc-401160-NIC-2 from Santa Cruz Biotechnology
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BMP-7 CRISPR Activation Plasmid (h) - sc-401160-ACT from Santa Cruz Biotechnology
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BMP-7 CRISPR Activation Plasmid (h2) - sc-401160-ACT-2 from Santa Cruz Biotechnology
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BMP-7 Lentiviral Activation Particles (h) - sc-401160-LAC from Santa Cruz Biotechnology
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BMP-7 Lentiviral Activation Particles (h2) - sc-401160-LAC-2 from Santa Cruz Biotechnology
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BMP-7 siRNA (h) - sc-39748 from Santa Cruz Biotechnology
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BMP-7 shRNA Plasmid (h) - sc-39748-SH from Santa Cruz Biotechnology
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BMP-7 shRNA (h) Lentiviral Particles - sc-39748-V from Santa Cruz Biotechnology
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BMP-7 RNAi - H00000655-R01 from Novus Biologicals
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MISSION® esiRNA - EHU038941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4006 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4006 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04982 from Sigma-Aldrich
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BMP7 siRNA (Human) - CRH0450 from Cohesion Biosciences
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BMP7 - MBS8229453 from MyBioSource
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shRNA set against Human BMP7 (NM_001719.2) - SHH247110 from Creative biogene
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Human BMP7 siRNA - orb260952 from Biorbyt
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BMP7 shRNA Plasmid (Human) - CHH0450 from Cohesion Biosciences
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BMP7 miRNA 3'UTR clone - MiUTR3H-00282 from Creative biogene
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