| Gene Symbol |
MOCOS
|
| Entrez Gene |
55034
|
| Alt Symbol |
HMCS, MCS, MOS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
molybdenum cofactor sulfurase
|
| Other Description |
MCS|MOS
|
| Swissprots |
Q9NWM7 Q53GP5 Q8N3A4 Q96EN8
|
| Accessions |
CAK32324 CAY77139 EAX01378 Q96EN8 AK000740 BAA91353 AK222886 BAD96606 AL834481 CAD39140 BC012079 AAH12079 BQ931455 DQ895841 ABM86767 EU176372 ABW03823 NM_017947 NP_060417
|
| Function |
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. {ECO:0000255|HAMAP-Rule:MF_03050, ECO:0000269|PubMed:16973608}.
|