Gene Symbol |
LAMB2
|
Entrez Gene |
3913
|
Alt Symbol |
LAMS, NPHS5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
laminin, beta 2 (laminin S)
|
Other Description |
S-LAM beta|S-laminin subunit beta|laminin B1s chain|laminin S|laminin subunit beta-2
|
Swissprots |
Q16321 P55268
|
Accessions |
CAA92279 EAW64958 EAW64959 P55268 AK094050 BAC04272 BC172384 AAI72384 BP354643 CN265778 CN265784 CV814167 S77512 AAB34682 X72760 CAA51288 X79683 CAA56130 XM_005265127 XP_005265184 NM_002292 NP_002283
|
Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane. Note=S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.
|
Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis
|