Gene Symbol | ENTPD3 |
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Entrez Gene | 956 |
Alt Symbol | CD39L3, HB6, NTPDase-3 |
Species | Human |
Gene Type | protein-coding |
Description | ectonucleoside triphosphate diphosphohydrolase 3 |
Other Description | CD39 antigen-like 3|NTPDase 3|ecto-ATP diphosphohydrolase 3|ecto-ATPDase 3|ecto-ATPase 3|ecto-apyrase 3 |
Swissprots | O75355 Q8N6K2 G5E9N0 B2R8D0 O60495 |
Accessions | EAW64600 EAW64601 O75355 AF034840 AAC09236 AF039917 AAC39884 AK313322 BAG36127 BC029869 AAH29869 BX952692 DA209533 XM_005265607 XP_005265664 XM_011534266 XP_011532568 XR_245167 XR_427297 XR_940520 NM_001248 NP_001239 NM_001291960 NP_001278889 NM_001291961 NP_001278890 |
Function | Has a threefold preference for the hydrolysis of ATP over ADP. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes. |
Top Pathways | Epstein-Barr virus infection, Purine metabolism, Pyrimidine metabolism |
CD39L3 CRISPR/Cas9 KO Plasmid (h) - sc-407470 from Santa Cruz Biotechnology
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CD39L3 HDR Plasmid (h) - sc-407470-HDR from Santa Cruz Biotechnology
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CD39L3 Double Nickase Plasmid (h) - sc-407470-NIC from Santa Cruz Biotechnology
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CD39L3 Double Nickase Plasmid (h2) - sc-407470-NIC-2 from Santa Cruz Biotechnology
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CD39L3 CRISPR Activation Plasmid (h) - sc-407470-ACT from Santa Cruz Biotechnology
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CD39L3 CRISPR Activation Plasmid (h2) - sc-407470-ACT-2 from Santa Cruz Biotechnology
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CD39L3 Lentiviral Activation Particles (h) - sc-407470-LAC from Santa Cruz Biotechnology
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CD39L3 Lentiviral Activation Particles (h2) - sc-407470-LAC-2 from Santa Cruz Biotechnology
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CD39L3 siRNA (h) - sc-78367 from Santa Cruz Biotechnology
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CD39L3 shRNA Plasmid (h) - sc-78367-SH from Santa Cruz Biotechnology
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CD39L3 shRNA (h) Lentiviral Particles - sc-78367-V from Santa Cruz Biotechnology
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CD39L3/ENTPD3 RNAi - H00000956-R01 from Novus Biologicals
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MISSION® esiRNA - EHU017071 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0188 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0187 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0189 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7891 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07826 from Sigma-Aldrich
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ENTPD3 siRNA (Human) - CRH0678 from Cohesion Biosciences
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ENTPD3 - MBS827388 from MyBioSource
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shRNA set against Human ENTPD3 (NM_001248.2) - SHH286049 from Creative biogene
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shRNA set against Human ENTPD3(NM_001248.2) - SHH034679 from Creative biogene
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Human ENTPD3 siRNA - orb261180 from Biorbyt
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ENTPD3 shRNA Plasmid (Human) - CHH0678 from Cohesion Biosciences
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