Gene Symbol | NEUROG3 |
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Entrez Gene | 50674 |
Alt Symbol | Atoh5, Math4B, NGN-3, bHLHa7, ngn3 |
Species | Human |
Gene Type | protein-coding |
Description | neurogenin 3 |
Other Description | class A basic helix-loop-helix protein 7|neurogenin-3|protein atonal homolog 5 |
Swissprots | Q9BY24 Q6DJX6 Q5VVI0 Q9Y4Z2 |
Accessions | AAK15022 CAB45384 EAW54328 Q9Y4Z2 AK313952 BAG36669 BC069098 AAH69098 BC074938 AAH74938 BC074939 AAH74939 BC117488 AAI17489 BC126468 AAI26469 EU446872 ABZ92401 GQ904714 ADM86144 HQ258759 ADR83510 NM_020999 NP_066279 |
Function | Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Top Pathways | Maturity onset diabetes of the young |
Neurogenin 3 CRISPR/Cas9 KO Plasmid (h) - sc-403619 from Santa Cruz Biotechnology
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Neurogenin 3 HDR Plasmid (h) - sc-403619-HDR from Santa Cruz Biotechnology
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Neurogenin 3 Double Nickase Plasmid (h) - sc-403619-NIC from Santa Cruz Biotechnology
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Neurogenin 3 Double Nickase Plasmid (h2) - sc-403619-NIC-2 from Santa Cruz Biotechnology
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Neurogenin 3 CRISPR Activation Plasmid (h) - sc-403619-ACT from Santa Cruz Biotechnology
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Neurogenin 3 CRISPR Activation Plasmid (h2) - sc-403619-ACT-2 from Santa Cruz Biotechnology
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Neurogenin 3 Lentiviral Activation Particles (h) - sc-403619-LAC from Santa Cruz Biotechnology
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Neurogenin 3 Lentiviral Activation Particles (h2) - sc-403619-LAC-2 from Santa Cruz Biotechnology
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Neurogenin 3 siRNA (h) - sc-42079 from Santa Cruz Biotechnology
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Neurogenin 3 shRNA Plasmid (h) - sc-42079-SH from Santa Cruz Biotechnology
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Neurogenin 3 shRNA (h) Lentiviral Particles - sc-42079-V from Santa Cruz Biotechnology
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Neurogenin-3 RNAi - H00050674-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15230 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15230 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02917 from Sigma-Aldrich
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NEUROG3 siRNA (Human) - CRH9400 from Cohesion Biosciences
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shRNA set against Human NEUROG3 (NM_020999.3) - SHH351624 from Creative biogene
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Human NEUROG3 siRNA - orb269902 from Biorbyt
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NEUROG3 shRNA Plasmid (Human) - CHH9400 from Cohesion Biosciences
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NEUROG3 miRNA 3'UTR clone - MiUTR4H-TG05968 from Creative biogene
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