| Gene Symbol |
ERMN
|
| Entrez Gene |
57471
|
| Alt Symbol |
JN, KIAA1189, ermin
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ermin, ERM-like protein
|
| Other Description |
ermin|juxtanodin
|
| Swissprots |
Q8TAM6 Q9ULN1 B4DKA6
|
| Accessions |
AAY14889 CCQ43640 EAX11448 Q8TAM6 AA736604 AB033015 BAA86503 AI207881 AK295051 BAG58100 AK295844 BAG58653 AK296477 BAG59118 AK296489 BAG59126 AV727436 BC026345 AAH26345 BI598234 DA248817 DA288720 DB576268 DC322056 DC331726 DC343891 DQ334271 ABC67251 HQ447390 ADQ31876 NM_001009959 NP_001009959 NM_001304344 NP_001291273 NM_001304345 NP_001291274 NM_001304346 NP_001291275 NM_020711 NP_065762
|
| Function |
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and liver. {ECO:0000269|PubMed:10574461}.
|
![Western Blot: ERMN Overexpression Lysate (Adult Normal) [NBL1-10334] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ERMN.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4298_ERMN%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10334-img0002.jpg)