Gene Symbol | FGF6 |
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Entrez Gene | 2251 |
Alt Symbol | HBGF-6, HST2 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 6 |
Other Description | FGF-6|HST-2|HSTF-2|heparin secretory-transforming protein 2|heparin-binding growth factor 6 |
Swissprots | P10767 Q0VAE1 |
Accessions | AAS79318 CAA40358 CAA40359 CAA40360 CAB37648 EAW88847 P10767 BC121097 AAI21098 BC121098 AAI21099 X63454 CAA45054 NM_020996 NP_066276 |
Function | Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. {ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Leukemia cell lines with platelet/ megakaryocytic differentiation potential. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-6 CRISPR/Cas9 KO Plasmid (h) - sc-405239 from Santa Cruz Biotechnology
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FGF-6 HDR Plasmid (h) - sc-405239-HDR from Santa Cruz Biotechnology
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FGF-6 Double Nickase Plasmid (h) - sc-405239-NIC from Santa Cruz Biotechnology
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FGF-6 Double Nickase Plasmid (h2) - sc-405239-NIC-2 from Santa Cruz Biotechnology
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FGF-6 CRISPR Activation Plasmid (h) - sc-405239-ACT from Santa Cruz Biotechnology
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FGF-6 CRISPR Activation Plasmid (h2) - sc-405239-ACT-2 from Santa Cruz Biotechnology
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FGF-6 Lentiviral Activation Particles (h) - sc-405239-LAC from Santa Cruz Biotechnology
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FGF-6 Lentiviral Activation Particles (h2) - sc-405239-LAC-2 from Santa Cruz Biotechnology
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FGF-6 siRNA (h) - sc-39454 from Santa Cruz Biotechnology
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FGF-6 shRNA Plasmid (h) - sc-39454-SH from Santa Cruz Biotechnology
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FGF-6 shRNA (h) Lentiviral Particles - sc-39454-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8663 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8663 from Sigma-Aldrich
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FGF6 siRNA (Human) - CRH1571 from Cohesion Biosciences
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FGF6 - MBS8212038 from MyBioSource
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FGF-6 CRISPR/Cas9 KO Plasmid (h2) - sc-405239-KO-2 from Santa Cruz Biotechnology
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FGF-6 HDR Plasmid (h2) - sc-405239-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FGF6 (NM_020996.1) - SHH294577 from Creative biogene
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shRNA set against Human FGF6(NM_020996.1) - SHH057876 from Creative biogene
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FGF6 shRNA Plasmid (Human) - CHH1571 from Cohesion Biosciences
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FGF6 miRNA 3'UTR clone - MiUTR1H-03634 from Creative biogene
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