| Gene Symbol |
TIAL1
|
| Entrez Gene |
7073
|
| Alt Symbol |
TCBP, TIAR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TIA1 cytotoxic granule-associated RNA binding protein-like 1
|
| Other Description |
T-cluster binding protein|TIA-1-related nucleolysin|aging-associated gene 7 protein|nucleolysin TIAR
|
| Swissprots |
A8K3T0 A8K4L9 Q01085
|
| Accessions |
EAW49385 EAW49386 EAW49387 EAW49388 Q01085 AA972022 AB209260 BAD92497 AK125264 AK290695 BAF83384 AK290984 BAF83673 AK291239 BAF83928 AK295243 BAG58235 AL833106 AW129760 AY633610 AAV33303 BC030025 AAH30025 BC128140 BC128141 D64015 BAA21559 M96954 AAA36384 XM_005270108 XP_005270165 XM_005270109 XP_005270166 XM_005270110 XP_005270167 XR_428715 XR_945808 NM_001033925 NP_001029097 NM_003252 NP_003243
|
| Function |
RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasmic granule. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Cytoplasmic granules of cytolytic T-lymphocytes. {ECO:0000250}.
|
![Western Blot: TIAL1 Overexpression Lysate (Adult Normal) [NBP2-04245] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TIAL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9998_TIAL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04245-img0001.jpg)