| Gene Symbol |
ENDOG
|
| Entrez Gene |
2021
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
endonuclease G
|
| Other Description |
endo G|endonuclease G, mitochondrial|mitochondrial endonuclease G
|
| Swissprots |
Q9BSP2 Q5T281 Q14249
|
| Accessions |
ADP90774 ADP90775 ADP90776 ADP90777 ADP90778 ADP90779 ADP90780 ADP90781 ADP90782 ADP90783 ADP90784 ADP90785 ADP90786 ADP90787 ADP90788 ADP90789 ADP90790 ADP90791 ADP90792 ADP90793 ADP90794 ADP90795 ADP90796 ADP90797 ADP90798 ADP90799 ADP90800 ADP90801 ADP90802 ADP90803 ADP90804 ADP90805 ADP90806 ADP90807 ADP90808 ADP90809 ADP90810 ADP90811 ADP90812 ADP90813 EAW87837 Q14249 AK130973 BC004922 AAH04922 BC016351 AAH16351 X79444 CAA55963 XM_011518347 XP_011516649 NM_004435 NP_004426
|
| Function |
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion.
|
| Top Pathways |
Apoptosis
|
![Western Blot: Endo G Overexpression Lysate (Adult Normal) [NBL1-10264] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Endo G.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5180_Endo%2520G%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10264-img0002.jpg)