Gene Symbol |
GGT2
|
Entrez Gene |
728441
|
Alt Symbol |
GGT, GGT 2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
gamma-glutamyltransferase 2
|
Other Description |
gamma-glutamyltranspeptidase 2|glutathione hydrolase 2|inactive gamma-glutamyltranspeptidase 2
|
Swissprots |
P36268
|
Accessions |
P36268 M30474 AAA52548 XM_005261888 XP_005261945 XM_005261890 XP_005261947 XM_006724392 XP_006724455 XM_006724395 XP_006724458 XM_006724396 XP_006724459 XM_011530603 XP_011528905 XM_011530604 XP_011528906 XM_011530605 XP_011528907 XM_011530606 XP_011528908 XM_011530607 XP_011528909 XM_011530608 XP_011528910 XM_011530609 XP_011528911 XM_011530610 XP_011528912 XM_011530611 XP_011528913 XM_011530612 XP_011528914 XM_011530613 XP_011528915 XM_011530614 XP_011528916 XM_011530615 XP_011528917 XM_011530616 XP_011528918 XM_011530617 XP_011528919 XM_011530618 XP_011528920 XM_011530619 XP_011528921 XM_011530620 XP_011528922 XM_011530621 XP_011528923 XM_011530622 XP_011528924 XR_938015
|
Function |
Isoform 1, isoform 2 and isoform 3 lack catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer. {ECO:0000269|PubMed:23682772}.
|
Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:23682772}. Endoplasmic reticulum {ECO:0000269|PubMed:23682772}. Note=Co-localizes with calnexin in the endoplasmic reticulum.
|
Tissue Specificity |
Highly expressed in fetal and adult kidney and liver.
|