Gene Symbol | ACTB |
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Entrez Gene | 60 |
Alt Symbol | BRWS1, PS1TP5BP1 |
Species | Human |
Gene Type | protein-coding |
Description | actin, beta |
Other Description | PS1TP5-binding protein 1|actin, cytoplasmic 1|beta cytoskeletal actin |
Swissprots | Q96HG5 Q96B34 Q75MN2 P60709 |
Accessions | AAA51567 AAP22343 AAS79319 AAX82251 CAI95947 CAR95103 CAS92761 CAY56012 EAW87341 EAW87343 P60709 AK025375 AK058019 AK098751 AK130062 AK130157 AK222925 BAD96645 AK223032 BAD96752 AK223055 BAD96775 AK225414 AK301372 BAG62914 AK304552 BAG65347 AK308277 AK309997 AK316361 BAH14732 BC001301 AAH01301 BC002409 AAH02409 BC004251 AAH04251 BC008633 AAH08633 BC009636 BC012854 AAH12854 BC013380 AAH13380 BC013835 BC014401 BC014861 AAH14861 BC016045 AAH16045 BC023204 BC113036 AAI13037 D28354 BAA05720 DQ407611 ABD66582 DQ471327 ABF01018 DQ890960 ABM81886 DQ894128 ABM85054 EF036500 ABO65086 EF095209 ABL01513 K00790 AAA51578 M28424 AAB16906 V00478 CAA23745 X00351 CAA25099 X63432 CAA45026 XM_006715764 XP_006715827 NM_001101 NP_001092 |
Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
Top Pathways | Hippo signaling pathway, Oxytocin signaling pathway, Salmonella infection, Proteoglycans in cancer, Influenza A |
β-Actin CRISPR/Cas9 KO Plasmid (h) - sc-400000 from Santa Cruz Biotechnology
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β-Actin HDR Plasmid (h) - sc-400000-HDR from Santa Cruz Biotechnology
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β-Actin Double Nickase Plasmid (h) - sc-400000-NIC from Santa Cruz Biotechnology
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β-Actin Double Nickase Plasmid (h2) - sc-400000-NIC-2 from Santa Cruz Biotechnology
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β-Actin CRISPR Activation Plasmid (h) - sc-400000-ACT from Santa Cruz Biotechnology
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β-Actin CRISPR Activation Plasmid (h2) - sc-400000-ACT-2 from Santa Cruz Biotechnology
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β-Actin Lentiviral Activation Particles (h) - sc-400000-LAC from Santa Cruz Biotechnology
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β-Actin Lentiviral Activation Particles (h2) - sc-400000-LAC-2 from Santa Cruz Biotechnology
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β-Actin siRNA (h) - sc-108069 from Santa Cruz Biotechnology
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β-Actin shRNA Plasmid (h) - sc-108069-SH from Santa Cruz Biotechnology
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β-Actin shRNA (h) Lentiviral Particles - sc-108069-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU073351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2768 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2768 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04802 from Sigma-Aldrich
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ACTB siRNA (Human) - CRH0047 from Cohesion Biosciences
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Beta-actin - MBS826828 from MyBioSource
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ACTB - MBS8211166 from MyBioSource
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β-Actin CRISPR/Cas9 KO Plasmid (h2) - sc-400000-KO-2 from Santa Cruz Biotechnology
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β-Actin HDR Plasmid (h2) - sc-400000-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ACTB(NM_001101.3) - SHG036233 from Creative biogene
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ACTB shRNA Plasmid (Human) - CHH0047 from Cohesion Biosciences
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ACTB miRNA 3'UTR clone - MiUTR1H-00132 from Creative biogene
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