| Gene Symbol |
CRLF3
|
| Entrez Gene |
51379
|
| Alt Symbol |
CREME-9, CREME9, CRLM9, CYTOR4, FRWS, p48.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytokine receptor-like factor 3
|
| Other Description |
cytokine receptor-like molecule 9|cytokine receptor-related protein 4|type I cytokine receptor-like factor p48
|
| Swissprots |
Q2MLY7 Q8IUI8 Q9UNI3 B2R8C3 Q9Y6M8 A6NJF3
|
| Accessions |
CCQ43529 EAW80297 Q8IUI8 AA993312 AF046059 AAD02422 AF120151 AAD31758 AK296238 BAG58957 AK313315 BAG36120 BC023567 AAH23567 BU902521 DQ298450 ABC55264 DQ892276 ABM83202 HQ447715 ADQ32200 XM_006721941 XP_006722004 XM_011524879 XP_011523181 NM_015986 NP_057070 NR_073118
|
| Function |
May play a role in the negative regulation of cell cycle progression. {ECO:0000269|PubMed:19427400}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19427400}. Note=The EGFP- and MYC-tagged protein has been shown to be cytoplasmic. {ECO:0000269|PubMed:19427400}.
|
| Tissue Specificity |
Expressed in several embryonic and adult tissues, including adult and fetal brain, liver, spleen and pancreas. Expressed in adult, but not fetal kidney. Expressed in skin and squamous cell carcinoma (SCC) and in several other cancer types. Also detected in lesion actinic keratosis (AK). {ECO:0000269|PubMed:16865251, ECO:0000269|PubMed:19427400}.
|
![Western Blot: CRLF3 Overexpression Lysate (Adult Normal) [NBL1-09486] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CRLF3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6981_CRLF3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09486-img0002.jpg)