Gene Symbol | GPRC5C |
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Entrez Gene | 55890 |
Alt Symbol | RAIG-3, RAIG3 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor, class C, group 5, member C |
Other Description | G protein-coupled receptor, family C, group 5, member C|G-protein coupled receptor family C group 5 member C|orphan G-protein coupled receptor|retinoic acid responsive gene protein|retinoic acid-induced gene 3 protein |
Swissprots | Q9NZG5 Q9NQ84 B5BUN4 Q2NL85 |
Accessions | CAI72095 EAW89160 EAW89161 EAW89162 EAW89163 EAW89164 Q9NQ84 AB451470 BAG70284 AF207989 AAF72870 AJ276102 CAC00633 AK000249 BAA91030 AK075397 BAC11595 AK097341 AK126429 AK131210 BAG54752 AK222909 BC004925 AAH04925 BC016860 AAH16860 BC069202 BC110848 AAI10849 BC125080 AAI25081 BC125081 AAI25082 BT007435 AAP36103 DQ891631 ABM82557 DQ894821 ABM85747 XM_005257512 XP_005257569 XM_005257514 XP_005257571 XM_011525022 XP_011523324 XM_011525023 XP_011523325 XM_011525024 XP_011523326 NM_018653 NP_061123 NM_022036 NP_071319 |
Function | This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles. |
Tissue Specificity | Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG). {ECO:0000269|PubMed:10945465, ECO:0000269|PubMed:11311935}. |
GPRC5C CRISPR/Cas9 KO Plasmid (h) - sc-406870 from Santa Cruz Biotechnology
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GPRC5C HDR Plasmid (h) - sc-406870-HDR from Santa Cruz Biotechnology
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GPRC5C Double Nickase Plasmid (h) - sc-406870-NIC from Santa Cruz Biotechnology
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GPRC5C Double Nickase Plasmid (h2) - sc-406870-NIC-2 from Santa Cruz Biotechnology
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GPRC5C CRISPR Activation Plasmid (h) - sc-406870-ACT from Santa Cruz Biotechnology
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GPRC5C CRISPR Activation Plasmid (h2) - sc-406870-ACT-2 from Santa Cruz Biotechnology
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GPRC5C Lentiviral Activation Particles (h) - sc-406870-LAC from Santa Cruz Biotechnology
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GPRC5C Lentiviral Activation Particles (h2) - sc-406870-LAC-2 from Santa Cruz Biotechnology
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GPRC5C siRNA (h) - sc-75196 from Santa Cruz Biotechnology
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GPRC5C shRNA Plasmid (h) - sc-75196-SH from Santa Cruz Biotechnology
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GPRC5C shRNA (h) Lentiviral Particles - sc-75196-V from Santa Cruz Biotechnology
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GPRC5C RNAi - H00055890-R04 from Novus Biologicals
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GPRC5C RNAi - H00055890-R03 from Novus Biologicals
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MISSION® esiRNA - EHU157441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9632 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9632 from Sigma-Aldrich
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GPRC5C siRNA (Human) - CRJ0993 from Cohesion Biosciences
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GPRC5C - MBS8227152 from MyBioSource
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shRNA set against Human GPRC5C (NM_018653.3) - SHH307210 from Creative biogene
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shRNA set against Human GPRC5C(NM_022036.2) - SHH101567 from Creative biogene
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shRNA set against Human GPRC5C(NM_018653.3) - SHH101585 from Creative biogene
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Human GPRC5C siRNA - orb271494 from Biorbyt
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GPRC5C shRNA Plasmid (Human) - CHJ0993 from Cohesion Biosciences
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GPRC5C miRNA 3'UTR clone - MiUTR1H-04233 from Creative biogene
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GPRC5C miRNA 3'UTR clone - MiUTR1H-04234 from Creative biogene
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