| Gene Symbol |
POC1A
|
| Entrez Gene |
25886
|
| Alt Symbol |
PIX2, SOFT, WDR51A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
POC1 centriolar protein A
|
| Other Description |
POC1 centriolar protein homolog A|WD repeat domain 51A|WD repeat-containing protein 51A|proteome of centriole protein 1A
|
| Swissprots |
Q0VDF8 A4FUW4 Q9UFJ8 Q96IK6 Q2TAK6 E9PFC6 Q8NBT0
|
| Accessions |
CAF86626 EAW65185 EAW65186 Q8NBT0 AF088072 AK075289 BAC11525 AK315688 BAG38051 AL117629 CAB56021 BC007417 AAH07417 BC110877 AAI10878 BC119692 AAI19693 BC119693 AAI19694 CA944751 XM_011533560 XP_011531862 XM_011533561 XP_011531863 XM_011533562 XP_011531864 XM_011533563 XP_011531865 XM_011533564 XP_011531866 XM_011533565 XP_011531867 XR_940401 XR_940402 XR_940403 NM_001161580 NP_001155052 NM_001161581 NP_001155053 NM_015426 NP_056241
|
| Function |
Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation. {ECO:0000269|PubMed:19109428, ECO:0000269|PubMed:23015594}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles.
|
![Western Blot: WDR51A Overexpression Lysate (Adult Normal) [NBP2-07180] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WDR51A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1755_WDR51A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07180-img0001.jpg)