Gene Symbol | ETV4 |
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Entrez Gene | 2118 |
Alt Symbol | E1A-F, E1AF, PEA3, PEAS3 |
Species | Human |
Gene Type | protein-coding |
Description | ets variant 4 |
Other Description | ETS translocation variant 4|EWS protein/E1A enhancer binding protein chimera|adenovirus E1A enhancer-binding protein|ets variant gene 4 (E1A enhancer-binding protein, E1AF)|polyomavirus enhancer activator 3 homolog |
Swissprots | B7Z5J3 B7Z9J6 Q96AW9 P43268 A8K314 |
Accessions | AAD09186 EAW51673 EAW51674 EAW51675 P43268 AK290429 BAF83118 AK298872 BAH12890 AK299019 BAH12929 AK312934 AK315961 BAH14332 BC007242 BC016623 AAH16623 BF304101 BM013535 BP268896 BU166857 CX783903 D12765 BAA02234 DB493072 DC375462 DQ396625 DQ396626 DQ892065 ABM82991 DQ895259 ABM86185 DR156106 EU693078 EU693079 U18018 AAA95991 XM_011524511 XP_011522813 XM_011524512 XP_011522814 XM_011524513 XP_011522815 XM_011524514 XP_011522816 NM_001079675 NP_001073143 NM_001261437 NP_001248366 NM_001261438 NP_001248367 NM_001261439 NP_001248368 NM_001986 NP_001977 |
Function | Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'. {ECO:0000269|PubMed:19307308}. |
Subcellular Location | Nucleus. |
Top Pathways | Transcriptional misregulation in cancer |
PEA3 CRISPR/Cas9 KO Plasmid (h) - sc-401704 from Santa Cruz Biotechnology
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PEA3 HDR Plasmid (h) - sc-401704-HDR from Santa Cruz Biotechnology
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PEA3 Double Nickase Plasmid (h) - sc-401704-NIC from Santa Cruz Biotechnology
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PEA3 Double Nickase Plasmid (h2) - sc-401704-NIC-2 from Santa Cruz Biotechnology
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PEA3 CRISPR Activation Plasmid (h) - sc-401704-ACT from Santa Cruz Biotechnology
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PEA3 CRISPR Activation Plasmid (h2) - sc-401704-ACT-2 from Santa Cruz Biotechnology
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PEA3 Lentiviral Activation Particles (h) - sc-401704-LAC from Santa Cruz Biotechnology
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PEA3 Lentiviral Activation Particles (h2) - sc-401704-LAC-2 from Santa Cruz Biotechnology
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PEA3 siRNA (h) - sc-36205 from Santa Cruz Biotechnology
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PEA3 shRNA Plasmid (h) - sc-36205-SH from Santa Cruz Biotechnology
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PEA3 shRNA (h) Lentiviral Particles - sc-36205-V from Santa Cruz Biotechnology
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Pea3 RNAi - H00002118-R01 from Novus Biologicals
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MISSION® esiRNA - EHU069441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8013 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8013 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05721 from Sigma-Aldrich
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ETV4 siRNA (Human) - CRH1471 from Cohesion Biosciences
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ETV4 - MBS8207096 from MyBioSource
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shRNA set against Human ETV4 (NM_001986.2) - SHH287717 from Creative biogene
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shRNA set against Human ETV4(NM_001986.2) - SHH040583 from Creative biogene
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Human ETV4 siRNA - orb261973 from Biorbyt
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ETV4 shRNA Plasmid (Human) - CHH1471 from Cohesion Biosciences
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ETV4 miRNA 3'UTR clone - MiUTR1H-03327 from Creative biogene
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ETV4 miRNA 3'UTR clone - MiUTR3H-03579 from Creative biogene
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