HPS5

Gene Symbol HPS5
Entrez Gene 11234
Alt Symbol AIBP63
Species Human
Gene Type protein-coding
Description Hermansky-Pudlak syndrome 5
Other Description Hermansky-Pudlak syndrome 5 protein|alpha integrin binding protein 63|alpha-integrin-binding protein 63|ruby-eye protein 2 homolog
Swissprots D3DQY0 Q8N4U0 O95942 A8K8S1 A8K6J8 Q9UPZ3 D3DQX9
Accessions EAW68402 EAW68403 EAW68404 EAW68405 EAW68406 EAW68407 Q9UPZ3 AA886415 AB023234 BAA76861 AF534400 AAO25962 AF534401 AAO25963 AF534402 AAO25964 AJ131721 CAB38232 AK024320 BAG51290 AK291663 BAF84352 AK292436 BAF85125 BC033640 AAH33640 XM_011519862 XP_011518164 XM_011519863 XP_011518165 XM_011519864 XP_011518166 XM_011519865 XP_011518167 XM_011519866 XP_011518168 XM_011519867 XP_011518169 XM_011519868 XP_011518170 XM_011519869 XP_011518171 XM_011519870 XP_011518172 XM_011519871 XP_011518173 NM_007216 NP_009147 NM_181507 NP_852608 NM_181508 NP_852609
Function May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins. {ECO:0000269|PubMed:15296495, ECO:0000269|PubMed:17301833}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:15030569}.
Tissue Specificity Widely expressed. Isoform 1:Highly expressed in lungs and testis. Isoform 2:Highly expressed in placenta, kidney, testis ovary, lung and thymus. {ECO:0000269|PubMed:15296495}.

HPS-5 (C-12) - sc-33384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HPS-5 (H-300) - sc-368137 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HPS-5 (N-15) - sc-33382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HPS-5 (N-15): sc-33382. Western blot analysis of HPS-5 expression in mouse liver tissue extract.

Anti-HPS5 antibody - ab22148 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-HPS5 antibody (ab22148) at 1/1000 dilutionLane 1 : Total protein extract from E. coli with ~50ng to 100ng of a negative control fusion protein with an irrelevant antigen at 20 ugLane 2 : Total protein extract from E. coli with ~50ng to 500ng of the antigen fusion protein at 20 ugSecondaryRabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution

Anti-HPS5 antibody - N-terminal - ab156199 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HPS5 antibody - N-terminal (ab156199) at 1/100 dilution + NCI-H292 cell lysate at 35 µg

Anti-HPS5 Antibody (aa88-116, APC) - LS-C236394 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116, Biotin) - LS-C236393 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116, AP) - LS-C236391 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116, FITC) - LS-C236395 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116, PE) - LS-C236396 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116, Azide-free, HRP) - LS-C249224 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116) - LS-C322090 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HPS5 Antibody (aa88-116) - LS-C157817 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HPS5 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The HPS5 antibody detected the HPS5 protein (arrow).

HPS5 Antibody - NBP1-86268 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HPS5 Antibody [NBP1-86268] - Staining of human testis shows strong cytoplasmic positivity in leydig cells.

Anti-HPS5 (826-840) antibody produced in rabbit - SAB1101369 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-HPS5 (826-840) : <B>Cat. No. SAB1101369</B>: Immunofluorescence of HUVEC cells using HPS5 (826-840) , Cat. No. SAB1101369 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-HPS5 antibody produced in rabbit - HPA037910 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HPS5: <B>Cat. No. HPA037910</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in leydig cells.

HPS5-Antibody-N-term - AP20048a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
HPS5 Antibody (N-term) (Cat. #AP20048a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HPS5 antibody detected the HPS5 protein (arrow).

HPS5 antibody [C1C2], Internal - GTX109784 from GeneTex

Host Rabbit
Clonality Polyclonal

HPS5 Antibody - N-terminal region (OAAB15452) - OAAB15452 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -HPS5 (Hermansky Pudlak Syndrome Protein 6, AIBP63, Alpha-integrin-binding protein63) - 211344 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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