| Gene Symbol |
TAF1D
|
| Entrez Gene |
79101
|
| Alt Symbol |
JOSD3, RAFI41, TAF(I)41, TAFI41
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
|
| Other Description |
Josephin domain containing 3|RNA polymerase I-specific TBP-associated factor 41 kDa|TATA box-binding protein-associated factor 1D|TATA box-binding protein-associated factor RNA polymerase I subunit D|TBP-associated factor 1D|transcription initiation factor SL1/TIF-IB subunit D
|
| Swissprots |
Q6I9Y6 Q9H5J8
|
| Accessions |
CCQ43712 EAW66912 EAW66913 EAW66914 Q9H5J8 AF086435 AF275800 AAG23815 AK027016 BAB15628 AK057183 AK128061 BC001972 AAH01972 BQ774057 CR457369 CAG33650 DW450227 HQ447355 ADQ31841 NM_024116 NP_077021
|
| Function |
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. {ECO:0000269|PubMed:15970593, ECO:0000269|PubMed:17318177}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:15520167, ECO:0000269|PubMed:17318177}.
|
![Western Blot: TAF1D Overexpression Lysate (Adult Normal) [NBL1-12110] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TAF1D.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8323_TAF1D%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12110-img0002.jpg)