| Gene Symbol |
Cyp3a2
|
| Entrez Gene |
266682
|
| Alt Symbol |
Cyp3a11
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 3, subfamily a, polypeptide 2
|
| Other Description |
CYPIIIA2|P450-PCN2|P450/6-beta-A|cytochrome P450 3A2|cytochrome P450, family 3, subfamily a, polypeptide 11|cytochrome P450-PCN2|cytochrome P450/6-beta-A|testosterone 6-beta-hydroxylase
|
| Swissprots |
Q64672 Q64629 Q5FVU5 P05183
|
| Accessions |
AAB60492 CAA55887 P05183 BC089765 AAH89765 FQ210312 FQ210941 M13646 AAA41051 U09742 AAA82168 X79320 CAA55888 NM_153312 NP_695224
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Expressed in liver. {ECO:0000269|PubMed:2398038, ECO:0000269|PubMed:7681660}.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Linoleic acid metabolism, Retinol metabolism
|