Gene Symbol |
CNPY2
|
Entrez Gene |
10330
|
Alt Symbol |
HP10390, MSAP, TMEM4, ZSIG9
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
canopy FGF signaling regulator 2
|
Other Description |
MIR-interacting saposin-like protein|canopy 2 homolog|protein canopy homolog 2|putative secreted protein Zsig9|transmembrane protein 4
|
Swissprots |
Q9UHE9 Q9Y2B0 B2R7B9
|
Accessions |
CAT04657 CAV30740 EAW96925 EAW96926 EAW96927 Q9Y2B0 AA515271 AB015631 BAA76498 AF186113 AAF01431 AK312921 BAG35766 AY032624 AAK38148 AY359102 AAQ89460 BC001027 AAH01027 BC065015 AAH65015 DA833421 HQ448080 ADQ32561 NM_001190991 NP_001177920 NM_014255 NP_055070
|
Function |
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
|
Subcellular Location |
Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138}.
|
Tissue Specificity |
Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas. {ECO:0000269|PubMed:12826659}.
|