Gene Symbol | CYP2S1 |
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Entrez Gene | 29785 |
Alt Symbol | CYPIIS1 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily S, polypeptide 1 |
Other Description | cytochrome P450 2S1|cytochrome P540, subfamily IIS, polypeptide 1 |
Swissprots | Q9BZ66 Q96SQ9 |
Accessions | EAW57019 EAW57020 EAW57021 Q96SQ9 AA316622 AF335278 AAK13498 AK027605 BAB55227 AK296087 BAG58842 AY358603 AAQ88966 BC033691 AAH33691 BP284240 BX422464 DQ893363 ABM84289 DQ896681 ABM87680 XR_935812 NM_030622 NP_085125 |
Function | Has a potential importance for extrahepatic xenobiotic metabolism. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:11181079}; Peripheral membrane protein {ECO:0000269|PubMed:11181079}. Microsome membrane {ECO:0000269|PubMed:11181079}; Peripheral membrane protein {ECO:0000269|PubMed:11181079}. |
Tissue Specificity | High level of expression in trachea, lung, stomach, small intestine, and spleen. {ECO:0000269|PubMed:11181079}. |
Top Pathways | Retinol metabolism, Metabolism of xenobiotics by cytochrome P450 |
CYP2S1 CRISPR/Cas9 KO Plasmid (h) - sc-405785 from Santa Cruz Biotechnology
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CYP2S1 HDR Plasmid (h) - sc-405785-HDR from Santa Cruz Biotechnology
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CYP2S1 Double Nickase Plasmid (h) - sc-405785-NIC from Santa Cruz Biotechnology
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CYP2S1 Double Nickase Plasmid (h2) - sc-405785-NIC-2 from Santa Cruz Biotechnology
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CYP2S1 CRISPR Activation Plasmid (h) - sc-405785-ACT from Santa Cruz Biotechnology
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CYP2S1 CRISPR Activation Plasmid (h2) - sc-405785-ACT-2 from Santa Cruz Biotechnology
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CYP2S1 Lentiviral Activation Particles (h) - sc-405785-LAC from Santa Cruz Biotechnology
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CYP2S1 Lentiviral Activation Particles (h2) - sc-405785-LAC-2 from Santa Cruz Biotechnology
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CYP2S1 siRNA (h) - sc-60483 from Santa Cruz Biotechnology
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CYP2S1 shRNA Plasmid (h) - sc-60483-SH from Santa Cruz Biotechnology
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CYP2S1 shRNA (h) Lentiviral Particles - sc-60483-V from Santa Cruz Biotechnology
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CYP2S1 RNAi - H00029785-R01 from Novus Biologicals
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MISSION® esiRNA - EHU079971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2498 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2498 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07861 from Sigma-Aldrich
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CYP2S1 siRNA (Human) - CRH9227 from Cohesion Biosciences
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CYP2S1 - MBS8205355 from MyBioSource
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CYP2S1 CRISPR/Cas9 KO Plasmid (h2) - sc-405785-KO-2 from Santa Cruz Biotechnology
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CYP2S1 HDR Plasmid (h2) - sc-405785-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CYP2S1(NM_030622.6) - SHG217243 from Creative biogene
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CYP2S1 shRNA Plasmid (Human) - CHH9227 from Cohesion Biosciences
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CYP2S1 miRNA 3'UTR clone - MiUTR1H-02627 from Creative biogene
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