Ffar3

Gene Symbol	Ffar3
Entrez Gene	233080
Alt Symbol	Gm478, Gpr41
Species	Mouse
Gene Type	protein-coding
Description	free fatty acid receptor 3
Other Description	G protein-coupled receptor 41|G-protein coupled receptor 41|putative G protein-coupled receptor GPR41
Swissprots	Q3UFD7
Accessions	EDL23982 Q3UFD7 AK148616 BAE28624 BC109330 AAI09331 BC125009 AAI25010 NM_001033316 NP_001028488
Function	G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. Activated by SCFAs and by beta-hydroxybutyrate, a ketone body produced by the liver upon starvation, it inhibits N-type calcium channels and modulates the activity of sympathetic neuro
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in white adipose tissue and skeletal muscle (at protein level). Abundantly expressed in sympathetic ganglia such as the superior cervical ganglion. Also expressed by intestinal endocrine cells. {ECO:0000269|PubMed:14722361, ECO:0000269|PubMed:18931303, ECO:0000269|PubMed:21518883, ECO:0000269|PubMed:22190648, ECO:0000269|PubMed:24748202}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Free Fatty Acid Receptor 3 (FFAR3), Mouse, ELISA Kit - SEA226Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 0.053ng/mL Range 0.156-10ng/mL

Free Fatty Acid Receptor 3, ELISA Kit - MBS048594 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Free Fatty Acid Receptor 3 (FFAR3) - SEA226Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse Free Fatty Acid Receptor 3 (FFAR3) ELISA Kit - EKU04273 from Biomatik Category ELISA Kit Prices $680.00, $3,028.00, $5,511.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.053 ng/mL Range 0.156-10 ng/mL

Mouse FFAR3 ELISA Kit - abx153996 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

Free Fatty Acid Receptor 3 (FFAR3), Mouse, ELISA Kit - DL-FFAR3-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

Mouse FFAR3 ELISA Kit - orb370713 from Biorbyt Category ELISA Kit Prices $519.00, $587.00 Sizes 48 test, 96 test Range Detection Range: 0.156-10ng/mL Detection low threshold: 0.053ng/mL

Mouse FFAR3 ELISA Kit - abx571708 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse Ffar3 ELISA Kit - E053440 from Biobool Category ELISA Kit

FFAR3 ELISA Kit (Mouse) (OKDD00839) - OKDD00839 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity <0.053ng/mL Range 0.156-10 ng/mL

Free Fatty Acid Receptor 3 (FFAR3), ELISA Kit - MBS455651 from MyBioSource Category ELISA Kit Prices $395.00, $520.00, $2,275.00, $4,420.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.053ng/mL Range 0.156-10ng/mL

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