Gene Symbol | GATAD2A |
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Entrez Gene | 54815 |
Alt Symbol | p66alpha |
Species | Human |
Gene Type | protein-coding |
Description | GATA zinc finger domain containing 2A |
Other Description | GATA zinc finger domain-containing protein 2A|transcriptional repressor p66-alpha |
Swissprots | Q7L3J2 Q86YP4 Q9NXS1 Q96F28 Q9NPU2 B5MC40 |
Accessions | EAW84819 EAW84820 EAW84821 EAW84822 EAW84823 Q86YP4 AK000092 BAA90939 AK024670 AK125974 AK225198 AK296781 BAG59359 AK303482 BAG64518 AK315416 AL390164 CAB99095 AY186731 AAO31797 BC009034 BC011684 AAH11684 BC012902 AAH12902 BG773264 BU632713 DB123918 DQ573509 EU446496 ABZ92025 XM_005259956 XP_005260013 XM_005259957 XP_005260014 XM_005259959 XP_005260016 XM_005259960 XP_005260017 XM_005259961 XP_005260018 XM_005259962 XP_005260019 XM_006722780 XP_006722843 XM_011528104 XP_011526406 XM_011528105 XP_011526407 XM_011528106 XP_011526408 XM_011528107 XP_011526409 XM_011528108 XP_011526410 NM_017660 NP_060130 NM_001300946 NP_001287875 |
Function | Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. {ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}. Note=Speckled nuclear localization requires both CR1 and CR2 regions. |
Tissue Specificity | Ubiquitous, both in fetal and adult tissues. {ECO:0000269|PubMed:12183469}. |
GATAD2A CRISPR/Cas9 KO Plasmid (h) - sc-405429 from Santa Cruz Biotechnology
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GATAD2A HDR Plasmid (h) - sc-405429-HDR from Santa Cruz Biotechnology
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GATAD2A Double Nickase Plasmid (h) - sc-405429-NIC from Santa Cruz Biotechnology
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GATAD2A Double Nickase Plasmid (h2) - sc-405429-NIC-2 from Santa Cruz Biotechnology
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GATAD2A CRISPR Activation Plasmid (h) - sc-405429-ACT from Santa Cruz Biotechnology
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GATAD2A CRISPR Activation Plasmid (h2) - sc-405429-ACT-2 from Santa Cruz Biotechnology
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GATAD2A Lentiviral Activation Particles (h) - sc-405429-LAC from Santa Cruz Biotechnology
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GATAD2A Lentiviral Activation Particles (h2) - sc-405429-LAC-2 from Santa Cruz Biotechnology
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GATAD2A siRNA (h) - sc-97791 from Santa Cruz Biotechnology
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GATAD2A shRNA Plasmid (h) - sc-97791-SH from Santa Cruz Biotechnology
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GATAD2A shRNA (h) Lentiviral Particles - sc-97791-V from Santa Cruz Biotechnology
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p66 alpha RNAi - H00054815-R01 from Novus Biologicals
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MISSION® esiRNA - EHU135231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9153 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9153 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09599 from Sigma-Aldrich
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GATAD2A siRNA (Human) - CRJ0237 from Cohesion Biosciences
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GATAD2A - MBS8213215 from MyBioSource
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shRNA set against Human GATAD2A (NM_017660.3) - SHH299606 from Creative biogene
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shRNA set against Human GATAD2A(NM_017660.3) - SHH078443 from Creative biogene
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Human GATAD2A siRNA - orb270738 from Biorbyt
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GATAD2A shRNA Plasmid (Human) - CHJ0237 from Cohesion Biosciences
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GATAD2A miRNA 3'UTR clone - MiUTR1H-03967 from Creative biogene
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