Gene Symbol | Pla2g2a |
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Entrez Gene | 18780 |
Alt Symbol | EF, Mom1, Pla2, sPLA2, sPla2-IIA |
Species | Mouse |
Gene Type | protein-coding |
Description | phospholipase A2, group IIA (platelets, synovial fluid) |
Other Description | GIIC sPLA2|enhancing factor|group IIA phospholipase A2|modifier of Min1|non-pancreatic secreted type II phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2 group IIa|phospholipase A2, membrane associated|secretory group II phospholipase A2 |
Swissprots | Q60871 P31482 |
Accessions | AAC52252 AHB62392 P31482 AK131857 BC045156 AAH45156 CB933893 U28244 AAB06315 U32359 AAB60494 X74266 CAA52325 NM_001082531 NP_001076000 NR_002926 NM_011108 |
Function | May play a role in cell proliferation, by increasing the binding of EGF to the cells and thereby modulating its action. In doing so, this isozyme binds to a membrane-associated receptor distinct from the EGF receptor and which could be a heparan- sulfate proteoglycan located on the cell membrane. |
Subcellular Location | Membrane; Peripheral membrane protein. |
Tissue Specificity | Mainly in the Paneth cells adjacent to the stem population in the small intestines. Also expressed in regenerating liver and hyperplastic esophageal epithelium. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
Recombinant Mouse PLA2G2A, CF - 4925-PL-010 from R&D Systems
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Recombinant Mouse Pla2g2a, His-tagged - Pla2g2a-670M from Creative Biomart
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Recombinant Mouse Phospholipase A2, membrane associated(Pla2g2a) - CSB-YP018091MO CSB-EP018091MO CSB-BP018091MO CSB-MP018091MO from Cusabio
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Recombinant Mouse PLA2G2A Protein, CF - 4925-PL from R&D Systems
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Phospholipase A2, membrane associated (Pla2g2a), Recombinant Protein - MBS955170 from MyBioSource
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Recombinant Mouse PLA2G2A Protein - PLA2G2A-12888M from Creative Biomart
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Recombinant Mouse PLA2G2A Protein, His-tagged - PLA2G2A-522M from Creative Biomart
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